Senna and Peritonitis - a phase IV clinical study of FDA data

Summary:

Peritonitis is reported as a side effect among people who take Senna (senna), especially for people who are male, 60+ old, have been taking the drug for 10+ years also take Lansoprazole, and have Pain.

The phase IV clinical study analyzes which people have Peritonitis when taking Senna. It is created by eHealthMe based on reports of 37,042 people who have side effects when taking Senna from the FDA, and is updated regularly.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

What is Peritonitis?

Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs) is found to be associated with 1,050 drugs and 1,576 conditions by eHealthMe. Check the latest studies of Peritonitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 26, 2026

37,042 people reported to have side effects when taking Senna.
Among them, 66 people (0.18%) have Peritonitis.

Among these 66 people:

How long have people been on Senna when they have Peritonitis? *

What is the gender of people who have Peritonitis when taking Senna? *

female: 50 %
male: 50 %

What is the age of people who have Peritonitis when taking Senna? *

What are other drugs people take besides Senna? *

What are other side effects people have besides Peritonitis? *

Gastrointestinal Perforation (hole in the digestive tract): 11 people, 16.67%
White Blood Cell Count Increased: 9 people, 13.64%
Abdominal Pain: 9 people, 13.64%
Large Intestine Perforation (hole in large intestine): 9 people, 13.64%
Diarrhea: 8 people, 12.12%
Neutrophil Count Increased (excess than normal number of neutrophil a type of blood cell): 8 people, 12.12%
Platelet Count Increased: 8 people, 12.12%
Ascites (accumulation of fluid in the abdominal cavity): 7 people, 10.61%
Gastric Cancer (stomach cancer): 7 people, 10.61%
General Physical Health Deterioration (weak health status): 7 people, 10.61%

What are the existing conditions these people have? *

Pain: 10 people, 15.15%
Nausea (feeling of having an urge to vomit): 9 people, 13.64%
High Blood Pressure: 7 people, 10.61%
Multiple Myeloma (cancer of the plasma cells): 7 people, 10.61%
Gastric Ulcer (stomach ulcer): 6 people, 9.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 9.09%
Parkinson's Disease: 5 people, 7.58%
Hyperkalemia (damage to or disease of the kidney): 4 people, 6.06%
Insomnia (sleeplessness): 4 people, 6.06%
Lung Cancer - Non-Small Cell (lung cancer): 4 people, 6.06%

* Approximation only. Some reports may have incomplete information.

Do you take Senna and have Peritonitis?

- Check whether Peritonitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Senna:

Senna (37,302 reports)

Peritonitis treatments and more:

Peritonitis (27,277 reports)

Browse all side effects of Senna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Peritonitis:

Peritonitis (1,050 drugs)

Browse all the conditions that are associated with Peritonitis:

Peritonitis (1,576 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on senna (the active ingredients of Senna) and Senna (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.