Senna and Platelet disorder - a phase IV clinical study of FDA data

Summary:

Platelet disorder is reported as a side effect among people who take Senna (senna), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Colace, and have Ovarian cancer.

The phase IV clinical study analyzes which people have Platelet disorder when taking Senna. It is created by eHealthMe based on reports of 37,042 people who have side effects when taking Senna from the FDA, and is updated regularly.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

What is Platelet disorder?

Platelet disorder is found to be associated with 321 drugs and 430 conditions by eHealthMe. Check the latest studies of Platelet disorder.



On Jul, 13, 2026

37,042 people reported to have side effects when taking Senna.
Among them, 15 people (0.04%) have Platelet disorder.

Could Senna cause Platelet disorder?

Among these 15 people:

How long have people been on Senna when they have Platelet disorder? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Platelet disorder when taking Senna? *

  • female: 64.29 %
  • male: 35.71 %

What is the age of people who have Platelet disorder when taking Senna? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 14.29 %
  • 40-49: 0.0 %
  • 50-59: 14.29 %
  • 60+: 71.43 %

What are other drugs people take besides Senna? *

  1. Zopiclone: 4 people, 26.67%
  2. Synthroid: 4 people, 26.67%
  3. Colace: 4 people, 26.67%
  4. Pantoprazole: 3 people, 20.00%
  5. Aranesp: 3 people, 20.00%
  6. Acyclovir: 2 people, 13.33%
  7. Rabeprazole: 2 people, 13.33%
  8. Protopic: 2 people, 13.33%
  9. Celexa: 2 people, 13.33%
  10. Clonazepam: 2 people, 13.33%

What are other side effects people have besides Platelet disorder? *

  1. Weight Decreased: 8 people, 53.33%
  2. Fall: 8 people, 53.33%
  3. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 7 people, 46.67%
  4. Stress And Anxiety: 6 people, 40.00%
  5. Weakness: 6 people, 40.00%
  6. Haemoglobin Decreased: 5 people, 33.33%
  7. White Blood Cell Count Decreased: 5 people, 33.33%
  8. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 4 people, 26.67%
  9. Heart Rate Irregular: 4 people, 26.67%
  10. Burning Sensation: 4 people, 26.67%

What are the existing conditions these people have? *

  1. Ovarian Cancer (cancer of ovary): 4 people, 26.67%
  2. Indigestion: 2 people, 13.33%
  3. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 13.33%
  4. Insomnia (sleeplessness): 2 people, 13.33%
  5. Parkinson's Disease: 2 people, 13.33%
  6. Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 13.33%
  7. High Blood Pressure: 2 people, 13.33%
  8. Headache (pain in head): 1 person, 6.67%
  9. Hypocalcaemia (levels of calcium in blood serum are abnormally low): 1 person, 6.67%
  10. Hypersensitivity: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Senna and have Platelet disorder?

- Check whether Platelet disorder is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Senna:

Platelet disorder treatments and more:

How severe was Platelet disorder and when was it recovered:

Expand to all the drugs that have ingredients of senna:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Senna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Platelet disorder:

Browse all the conditions that are associated with Platelet disorder:


How the study uses the data?

The study uses data from the FDA. It is based on senna (the active ingredients of Senna) and Senna (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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