Senna and Skin erosion - a phase IV clinical study of FDA data

Summary:

Skin erosion is reported as a side effect among people who take Senna (senna), especially for people who are male, 60+ old, also take Amlodipine, and have High blood pressure.

The phase IV clinical study analyzes which people have Skin erosion when taking Senna. It is created by eHealthMe based on reports of 37,042 people who have side effects when taking Senna from the FDA, and is updated regularly.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

What is Skin erosion?

Skin erosion (a discontinuity of the skin) is found to be associated with 360 drugs and 526 conditions by eHealthMe. Check the latest studies of Skin erosion.

On Jul, 04, 2026

37,042 people reported to have side effects when taking Senna.
Among them, 16 people (0.04%) have Skin erosion.

Among these 16 people:

What is the gender of people who have Skin erosion when taking Senna? *

female: 50 %
male: 50 %

What is the age of people who have Skin erosion when taking Senna? *

What are other drugs people take besides Senna? *

What are other side effects people have besides Skin erosion? *

Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 12 people, 75.00%
Itching: 9 people, 56.25%
Wound Infection: 6 people, 37.50%
Circulatory Collapse: 6 people, 37.50%
Oedema Peripheral (superficial swelling): 6 people, 37.50%
Chronic Renal Failure (kidney failure): 6 people, 37.50%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 37.50%
Pain: 6 people, 37.50%
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 6 people, 37.50%
Anaemia (lack of blood): 6 people, 37.50%

What are the existing conditions these people have? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 6 people, 37.50%
High Blood Pressure: 6 people, 37.50%
Essential Hypertension (primary hypertension): 5 people, 31.25%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 5 people, 31.25%
Chest Pain: 5 people, 31.25%
Nephrogenic Anaemia (anaemia due to kidney disease): 1 person, 6.25%
Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 1 person, 6.25%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Senna and have Skin erosion?

- Check whether Skin erosion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Senna:

Senna (37,302 reports)

Skin erosion treatments and more:

Skin erosion (3,354 reports)

Browse all side effects of Senna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Skin erosion:

Skin erosion (360 drugs)

Browse all the conditions that are associated with Skin erosion:

Skin erosion (526 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on senna (the active ingredients of Senna) and Senna (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.