Senna and Spinal fusion surgery - a phase IV clinical study of FDA data

Summary:

Spinal fusion surgery is reported as a side effect among people who take Senna (senna), especially for people who are female, 60+ old, also take Miralax, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Spinal fusion surgery when taking Senna. It is created by eHealthMe based on reports of 37,042 people who have side effects when taking Senna from the FDA, and is updated regularly.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

What is Spinal fusion surgery?

Spinal fusion surgery is found to be associated with 493 drugs and 420 conditions by eHealthMe. Check the latest studies of Spinal fusion surgery.

On Jul, 10, 2026

37,042 people reported to have side effects when taking Senna.
Among them, 34 people (0.09%) have Spinal fusion surgery.

Could Senna cause Spinal fusion surgery?

Among these 34 people:

What is the gender of people who have Spinal fusion surgery when taking Senna? *

female: 61.76 %
male: 38.24 %

What is the age of people who have Spinal fusion surgery when taking Senna? *

What are other drugs people take besides Senna? *

What are other side effects people have besides Spinal fusion surgery? *

Pain: 24 people, 70.59%
Back Pain: 23 people, 67.65%
Weakness: 18 people, 52.94%
Dyspnea (difficult or laboured breathing): 18 people, 52.94%
Joint Swelling: 18 people, 52.94%
Spinal Compression Fracture (fracture due to spinal compression on bone): 18 people, 52.94%
Spinal Cord Compression: 18 people, 52.94%
Stress And Anxiety: 18 people, 52.94%
Joint Pain: 18 people, 52.94%
Kyphosis (a condition of over-curvature of the thoracic vertebrae (upper back)): 17 people, 50.00%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 10 people, 29.41%
Stress And Anxiety: 8 people, 23.53%
Metastases To Bone (cancer spreads to bone): 8 people, 23.53%
Pain: 5 people, 14.71%
Osteoporosis (bones weak and more likely to break): 5 people, 14.71%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 5.88%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 5.88%
Stable Angina (a constant chest pain): 1 person, 2.94%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 2.94%
Parkinson's Disease: 1 person, 2.94%

* Approximation only. Some reports may have incomplete information.

Do you take Senna and have Spinal fusion surgery?

- Check whether Spinal fusion surgery is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Senna:

Senna (37,302 reports)

Browse all side effects of Senna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Spinal fusion surgery:

Spinal fusion surgery (493 drugs)

Browse all the conditions that are associated with Spinal fusion surgery:

Spinal fusion surgery (420 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on senna (the active ingredients of Senna) and Senna (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.