Sennosides and Eosinophil count increased - a phase IV clinical study of FDA data

Summary:

Eosinophil count increased is reported as a side effect among people who take Sennosides (senna), especially for people who are male, 40-49 old, also take Zopiclone, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Eosinophil count increased when taking Sennosides. It is created by eHealthMe based on reports of 8,186 people who have side effects when taking Sennosides from the FDA, and is updated regularly.

What is Sennosides?

Sennosides has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 8,247 Sennosides users. Check the latest studies of Sennosides.

What is Eosinophil count increased?

Eosinophil count increased is found to be associated with 770 drugs and 1,130 conditions by eHealthMe. Check the latest studies of Eosinophil count increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

8,186 people reported to have side effects when taking Sennosides.
Among them, 15 people (0.18%) have Eosinophil count increased.

Could Sennosides cause Eosinophil count increased?

Among these 15 people:

What is the gender of people who have Eosinophil count increased when taking Sennosides? *

female: 33.33 %
male: 66.67 %

What is the age of people who have Eosinophil count increased when taking Sennosides? *

What are other drugs people take besides Sennosides? *

What are other side effects people have besides Eosinophil count increased? *

Haemoglobin Decreased: 11 people, 73.33%
Haematocrit Decreased: 8 people, 53.33%
Dyspnea (difficult or laboured breathing): 8 people, 53.33%
White Blood Cells Urine Positive: 7 people, 46.67%
Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 7 people, 46.67%
Monocyte Percentage Increased: 7 people, 46.67%
Lymphopenia (an abnormally low level of lymphocytes in the blood): 7 people, 46.67%
Lymphocyte Percentage Decreased: 7 people, 46.67%
Lung Disorder (lung disease): 7 people, 46.67%
Leukopenia (less number of white blood cells in blood): 7 people, 46.67%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 46.67%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 20.00%
Glioblastoma Multiforme (most common and deadliest of malignant primary brain tumours in adults): 2 people, 13.33%
Urinary Tract Infection: 1 person, 6.67%
Skin Ulcer: 1 person, 6.67%
Psychotic Disorder: 1 person, 6.67%
Muscle Contracture (a permanent shortening of a muscle): 1 person, 6.67%
Insomnia (sleeplessness): 1 person, 6.67%
Herpes Zoster: 1 person, 6.67%
Haemorrhoidal Haemorrhage (bleeding from the haemorrhoids): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Sennosides and have Eosinophil count increased?

- Check whether Eosinophil count increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sennosides:

Sennosides (8,247 reports)

Browse all side effects of Sennosides:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Eosinophil count increased:

Eosinophil count increased (770 drugs)

Browse all the conditions that are associated with Eosinophil count increased:

Eosinophil count increased (1,130 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on senna (the active ingredients of Sennosides) and Sennosides (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.