Sennosides and Hot flush - a phase IV clinical study of FDA data

Summary:

Hot flush is reported as a side effect among people who take Sennosides (senna), especially for people who are 60+ old, also take Metformin, and have Acromegaly.

The phase IV clinical study analyzes which people have Hot flush when taking Sennosides. It is created by eHealthMe based on reports of 8,186 people who have side effects when taking Sennosides from the FDA, and is updated regularly.

What is Sennosides?

Sennosides has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 8,247 Sennosides users. Check the latest studies of Sennosides.

What is Hot flush?

Hot flush (sudden feelings of heat) is found to be associated with 1,771 drugs and 2,347 conditions by eHealthMe. Check the latest studies of Hot flush.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

8,186 people reported to have side effects when taking Sennosides.
Among them, 31 people (0.38%) have Hot flush.

Among these 31 people:

What is the age of people who have Hot flush when taking Sennosides? *

What are other drugs people take besides Sennosides? *

What are other side effects people have besides Hot flush? *

Fatigue (feeling of tiredness): 25 people, 80.65%
Headache (pain in head): 23 people, 74.19%
Pain: 23 people, 74.19%
Weakness: 22 people, 70.97%
Back Pain: 22 people, 70.97%
Fall: 21 people, 67.74%
Dizziness: 16 people, 51.61%
Wound: 13 people, 41.94%
Cough: 13 people, 41.94%
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 13 people, 41.94%

What are the existing conditions these people have? *

High Blood Pressure: 13 people, 41.94%
Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 13 people, 41.94%
Primary Progressive Multiple Sclerosis (primary progressive inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 9 people, 29.03%
Joint Pain: 8 people, 25.81%
Prostate Cancer: 3 people, 9.68%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 6.45%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 3.23%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 1 person, 3.23%
Metastases To Breast (cancer spreads to brain): 1 person, 3.23%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Sennosides and have Hot flush?

- Check whether Hot flush is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sennosides:

Sennosides (8,247 reports)

Hot flush treatments and more:

Hot flush (91,208 reports)

Browse all side effects of Sennosides:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hot flush:

Hot flush (1,771 drugs)

Browse all the conditions that are associated with Hot flush:

Hot flush (2,347 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on senna (the active ingredients of Sennosides) and Sennosides (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.