Septra ds and Hypothyroidism - a phase IV clinical study of FDA data

Summary:

Hypothyroidism is reported as a side effect among people who take Septra ds (sulfamethoxazole; trimethoprim), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Lasix, and have Depression.

The phase IV clinical study analyzes which people have Hypothyroidism when taking Septra ds. It is created by eHealthMe based on reports of 2,191 people who have side effects when taking Septra ds from the FDA, and is updated regularly.

What is Septra ds?

Septra ds has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 2,349 Septra ds users. Check the latest studies of Septra ds.

What is Hypothyroidism?

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development) is found to be associated with 1,617 drugs and 2,600 conditions by eHealthMe. Check the latest studies of Hypothyroidism.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 27, 2026

2,191 people reported to have side effects when taking Septra ds.
Among them, 27 people (1.23%) have Hypothyroidism.

Among these 27 people:

How long have people been on Septra ds when they have Hypothyroidism? *

What is the gender of people who have Hypothyroidism when taking Septra ds? *

female: 78.26 %
male: 21.74 %

What is the age of people who have Hypothyroidism when taking Septra ds? *

What are other drugs people take besides Septra ds? *

What are other side effects people have besides Hypothyroidism? *

Stress And Anxiety: 19 people, 70.37%
Lactose Intolerance (inability to digest lactose): 17 people, 62.96%
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 17 people, 62.96%
Fever: 17 people, 62.96%
Constipation: 16 people, 59.26%
Weakness: 16 people, 59.26%
Swallowing Pain Or Burning: 16 people, 59.26%
High Blood Pressure: 16 people, 59.26%
Nausea (feeling of having an urge to vomit): 16 people, 59.26%
Acute Kidney Failure: 16 people, 59.26%

What are the existing conditions these people have? *

Stress And Anxiety: 4 people, 14.81%
Insomnia (sleeplessness): 4 people, 14.81%
High Blood Pressure: 4 people, 14.81%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 14.81%
Depression: 4 people, 14.81%
Renal Cell Carcinoma (a kidney cancer): 2 people, 7.41%
Acute Promyelocytic Leukaemia (cancer of the blood and bone marrow): 2 people, 7.41%
Renal Disorder (kidney disease): 1 person, 3.70%
Pain: 1 person, 3.70%
Osteoporosis (bones weak and more likely to break): 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Septra ds and have Hypothyroidism?

- Check whether Hypothyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Septra ds:

Septra ds (2,349 reports)

Hypothyroidism treatments and more:

Hypothyroidism (168,067 reports)

How severe was Hypothyroidism and when was it recovered:

Hypothyroidism in Septra ds

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Hypothyroidism and drugs with ingredients of sulfamethoxazole; trimethoprim (627 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Septra ds:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypothyroidism:

Hypothyroidism (1,617 drugs)

Browse all the conditions that are associated with Hypothyroidism:

Hypothyroidism (2,600 conditions)

Related publications that referenced our studies

Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .
Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Septra ds) and Septra ds (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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