Septra and Diastolic dysfunction - a phase IV clinical study of FDA data

Summary:

Diastolic dysfunction is reported as a side effect among people who take Septra (sulfamethoxazole; trimethoprim), especially for people who are male, 50-59 old, also take Diflucan, and have Interstitial lung disease.

The phase IV clinical study analyzes which people have Diastolic dysfunction when taking Septra. It is created by eHealthMe based on reports of 9,928 people who have side effects when taking Septra from the FDA, and is updated regularly.

What is Septra?

Septra has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 10,280 Septra users. Check the latest studies of Septra.

What is Diastolic dysfunction?

Diastolic dysfunction is found to be associated with 682 drugs and 630 conditions by eHealthMe. Check the latest studies of Diastolic dysfunction.

On Jun, 22, 2026

9,928 people reported to have side effects when taking Septra.
Among them, 32 people (0.32%) have Diastolic dysfunction.

Could Septra cause Diastolic dysfunction?

Among these 32 people:

What is the gender of people who have Diastolic dysfunction when taking Septra? *

female: 36 %
male: 64 %

What is the age of people who have Diastolic dysfunction when taking Septra? *

What are other drugs people take besides Septra? *

What are other side effects people have besides Diastolic dysfunction? *

Dyspnea (difficult or laboured breathing): 24 people, 75.00%
Cough: 23 people, 71.88%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 20 people, 62.50%
Haematuria (presence of blood in urine): 20 people, 62.50%
Nausea And Vomiting: 20 people, 62.50%
Musculoskeletal Chest Pain (pain in chest muscle or nerve or bones): 20 people, 62.50%
Pneumonia: 19 people, 59.38%
Skin Ulcer: 18 people, 56.25%
Osteoporosis (bones weak and more likely to break): 18 people, 56.25%
Localised Infection (infection at the single location): 18 people, 56.25%

What are the existing conditions these people have? *

Interstitial Lung Disease: 17 people, 53.12%
Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 16 people, 50.00%
Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 11 people, 34.38%
Multiple Myeloma (cancer of the plasma cells): 2 people, 6.25%
Acute Promyelocytic Leukaemia (cancer of the blood and bone marrow): 2 people, 6.25%
Bone Loss: 1 person, 3.12%
Breast Cancer: 1 person, 3.12%
Blood Triglycerides Decreased: 1 person, 3.12%
Cardiomyopathy (weakening of the heart muscle): 1 person, 3.12%
Impaired Gastric Emptying: 1 person, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Septra and have Diastolic dysfunction?

- Check whether Diastolic dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Septra:

Septra (10,280 reports)

Diastolic dysfunction treatments and more:

Diastolic dysfunction (4,665 reports)

How severe was Diastolic dysfunction and when was it recovered:

Diastolic dysfunction in Septra

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Diastolic dysfunction and drugs with ingredients of sulfamethoxazole; trimethoprim

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Septra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diastolic dysfunction:

Diastolic dysfunction (682 drugs)

Browse all the conditions that are associated with Diastolic dysfunction:

Diastolic dysfunction (630 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Septra) and Septra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.