Septra and Encephalitis - a phase IV clinical study of FDA data

Summary:

Encephalitis is reported as a side effect among people who take Septra (sulfamethoxazole; trimethoprim), especially for people who are female, 2-9 old, have been taking the drug for < 1 month also take Prednisone, and have Psoriatic arthropathy.

The phase IV clinical study analyzes which people have Encephalitis when taking Septra. It is created by eHealthMe based on reports of 9,928 people who have side effects when taking Septra from the FDA, and is updated regularly.

What is Septra?

Septra has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 10,280 Septra users. Check the latest studies of Septra.

What is Encephalitis?

Encephalitis (inflammation of the brain) is found to be associated with 660 drugs and 844 conditions by eHealthMe. Check the latest studies of Encephalitis.



On Jul, 21, 2026

9,928 people reported to have side effects when taking Septra.
Among them, 20 people (0.2%) have Encephalitis.

Could Septra cause Encephalitis?

Among these 20 people:

How long have people been on Septra when they have Encephalitis? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Encephalitis when taking Septra? *

  • female: 57.89 %
  • male: 42.11 %

What is the age of people who have Encephalitis when taking Septra? *

  • 0-1: 0.0 %
  • 2-9: 40.0 %
  • 10-19: 20.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 6.67 %
  • 50-59: 33.33 %
  • 60+: 0.0 %

What are other drugs people take besides Septra? *

  1. Prednisone: 8 people, 40.00%
  2. Prograf: 6 people, 30.00%
  3. Cyclosporine: 5 people, 25.00%
  4. Prilosec: 5 people, 25.00%
  5. Aspirin: 5 people, 25.00%
  6. Methotrexate: 4 people, 20.00%
  7. Humira: 4 people, 20.00%
  8. Cellcept: 3 people, 15.00%
  9. Toviaz: 3 people, 15.00%
  10. Zenapax: 3 people, 15.00%

What are other side effects people have besides Encephalitis? *

  1. Diarrhea: 5 people, 25.00%
  2. Brain Oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 4 people, 20.00%
  3. Drug Ineffective: 4 people, 20.00%
  4. Abdominal Pain: 4 people, 20.00%
  5. Encephalitis Viral (inflammation of the brain due to viral infection): 4 people, 20.00%
  6. Oral Intake Reduced: 3 people, 15.00%
  7. Cough: 3 people, 15.00%
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 15.00%
  9. Cerebral Ventricle Dilatation (enlargement of ventricle of brain): 3 people, 15.00%
  10. Joint Swelling: 3 people, 15.00%

What are the existing conditions these people have? *

  1. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 15.00%
  2. Upper Limb Fracture: 1 person, 5.00%
  3. T-Cell Type Acute Leukaemia (a form of cancer of the white blood cells): 1 person, 5.00%
  4. Streptococcus Test Positive: 1 person, 5.00%
  5. Skin Disorder (skin disease): 1 person, 5.00%
  6. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 5.00%
  7. Pain: 1 person, 5.00%
  8. Oral Pain: 1 person, 5.00%
  9. Hepatitis C: 1 person, 5.00%
  10. Device Occlusion: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Septra and have Encephalitis?

- Check whether Encephalitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Septra:

Encephalitis treatments and more:

How severe was Encephalitis and when was it recovered:

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Septra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Encephalitis:

Browse all the conditions that are associated with Encephalitis:


How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Septra) and Septra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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