Sertraline and Crystal urine present - a phase IV clinical study of FDA data

Summary:

Crystal urine present is reported as a side effect among people who take Sertraline (sertraline hydrochloride), especially for people who are male, 0-1 old, also take Abilify, and have Bipolar disorder.

The phase IV clinical study analyzes which people have Crystal urine present when taking Sertraline. It is created by eHealthMe based on reports of 146,463 people who have side effects when taking Sertraline from the FDA, and is updated regularly.

What is Sertraline?

Sertraline has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 153,305 Sertraline users. Check the latest studies of Sertraline.

What is Crystal urine present?

Crystal urine present is found to be associated with 107 drugs and 168 conditions by eHealthMe. Check the latest studies of Crystal urine present.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

146,463 people reported to have side effects when taking Sertraline.
Among them, 11 people (0.01%) have Crystal urine present.

Could Sertraline cause Crystal urine present?

Among these 11 people:

What is the gender of people who have Crystal urine present when taking Sertraline? *

female: 20 %
male: 80 %

What is the age of people who have Crystal urine present when taking Sertraline? *

What are other drugs people take besides Sertraline? *

What are other side effects people have besides Crystal urine present? *

Hypernatraemia (an abnormally high plasma concentration of sodium ions): 9 people, 81.82%
Extremity Necrosis (death of body tissue of arms and legs): 9 people, 81.82%
Weight Decreased: 9 people, 81.82%
Heart Rate Increased: 9 people, 81.82%
Dehydration (dryness resulting from the removal of water): 9 people, 81.82%
Thrombosis (formation of a blood clot inside a blood vessel): 9 people, 81.82%
Drowsiness: 9 people, 81.82%
Foot Amputation (loss of foot): 9 people, 81.82%
Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 4 people, 36.36%
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 2 people, 18.18%

What are the existing conditions these people have? *

Bipolar Disorder (mood disorder): 8 people, 72.73%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 9.09%
Insomnia (sleeplessness): 1 person, 9.09%
Hypotension (abnormally low blood pressure): 1 person, 9.09%
Diabetes: 1 person, 9.09%
Constipation: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Sertraline and have Crystal urine present?

- Check whether Crystal urine present is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sertraline:

Sertraline (153,305 reports)

Browse all side effects of Sertraline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Crystal urine present:

Crystal urine present (107 drugs)

Browse all the conditions that are associated with Crystal urine present:

Crystal urine present (168 conditions)

Related publications that referenced our studies

Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on sertraline hydrochloride (the active ingredients of Sertraline) and Sertraline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.