Sertraline and Encephalitis - a phase IV clinical study of FDA data

Summary:

Encephalitis is reported as a side effect among people who take Sertraline (sertraline hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Naproxen, and have Psoriasis.

The phase IV clinical study analyzes which people have Encephalitis when taking Sertraline. It is created by eHealthMe based on reports of 146,463 people who have side effects when taking Sertraline from the FDA, and is updated regularly.

What is Sertraline?

Sertraline has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 153,304 Sertraline users. Check the latest studies of Sertraline.

What is Encephalitis?

Encephalitis (inflammation of the brain) is found to be associated with 662 drugs and 844 conditions by eHealthMe. Check the latest studies of Encephalitis.

On Jul, 18, 2026

146,463 people reported to have side effects when taking Sertraline.
Among them, 58 people (0.04%) have Encephalitis.

Among these 58 people:

How long have people been on Sertraline when they have Encephalitis? *

What is the gender of people who have Encephalitis when taking Sertraline? *

female: 57.14 %
male: 42.86 %

What is the age of people who have Encephalitis when taking Sertraline? *

What are other drugs people take besides Sertraline? *

What are other side effects people have besides Encephalitis? *

Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 10 people, 17.24%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 10 people, 17.24%
Neonatal Asphyxia (a condition in which an extreme decrease in the concentration of oxygen in the body accompanied by an increase in the concentration of carbon dioxide in neonate): 9 people, 15.52%
Weakness: 9 people, 15.52%
Fall: 9 people, 15.52%
Brain Oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 9 people, 15.52%
Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 9 people, 15.52%
Septic Arthritis Staphylococcal (bacterial blood infection spreads to joint caused by staphylococcus): 9 people, 15.52%
Confusional State: 8 people, 13.79%
Dizziness: 6 people, 10.34%

What are the existing conditions these people have? *

Interstitial Lung Disease: 9 people, 15.52%
Psoriasis (immune-mediated disease that affects the skin): 9 people, 15.52%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 10.34%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 5 people, 8.62%
Ill-Defined Disorder: 5 people, 8.62%
Panic Reaction: 4 people, 6.90%
Fungal Abscess Central Nervous System (collection of pus in brain by result of fungal infection): 4 people, 6.90%
Psychotic Disorder: 2 people, 3.45%
Lung Cancer - Non-Small Cell (lung cancer): 2 people, 3.45%
Diabetes: 2 people, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Sertraline and have Encephalitis?

- Check whether Encephalitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sertraline:

Sertraline (153,304 reports)

Encephalitis treatments and more:

Encephalitis (9,372 reports)

Browse all side effects of Sertraline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Encephalitis:

Encephalitis (662 drugs)

Browse all the conditions that are associated with Encephalitis:

Encephalitis (844 conditions)

Related publications that referenced our studies

Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on sertraline hydrochloride (the active ingredients of Sertraline) and Sertraline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.