Sertraline and Increased upper airway secretion - a phase IV clinical study of FDA data

Summary:

Increased upper airway secretion is reported as a side effect among people who take Sertraline (sertraline hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Metoprolol Tartrate, and have Asthma.

The phase IV clinical study analyzes which people have Increased upper airway secretion when taking Sertraline. It is created by eHealthMe based on reports of 146,463 people who have side effects when taking Sertraline from the FDA, and is updated regularly.

What is Sertraline?

Sertraline has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 153,305 Sertraline users. Check the latest studies of Sertraline.

What is Increased upper airway secretion?

Increased upper airway secretion is found to be associated with 616 drugs and 627 conditions by eHealthMe. Check the latest studies of Increased upper airway secretion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

146,463 people reported to have side effects when taking Sertraline.
Among them, 38 people (0.03%) have Increased upper airway secretion.

Could Sertraline cause Increased upper airway secretion?

Among these 38 people:

How long have people been on Sertraline when they have Increased upper airway secretion? *

What is the gender of people who have Increased upper airway secretion when taking Sertraline? *

female: 63.89 %
male: 36.11 %

What is the age of people who have Increased upper airway secretion when taking Sertraline? *

What are other drugs people take besides Sertraline? *

What are other side effects people have besides Increased upper airway secretion? *

Dyspnea (difficult or laboured breathing): 14 people, 36.84%
Cough: 13 people, 34.21%
Chest Pain: 12 people, 31.58%
Fatigue (feeling of tiredness): 12 people, 31.58%
Nausea (feeling of having an urge to vomit): 10 people, 26.32%
Fever: 9 people, 23.68%
Nasopharyngitis (inflammation of the nasopharynx): 9 people, 23.68%
Throat Irritation: 8 people, 21.05%
Asthma: 8 people, 21.05%
Headache (pain in head): 8 people, 21.05%

What are the existing conditions these people have? *

Asthma: 12 people, 31.58%
Bipolar Disorder (mood disorder): 5 people, 13.16%
Pain: 4 people, 10.53%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 10.53%
High Blood Cholesterol: 3 people, 7.89%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 7.89%
High Blood Pressure: 3 people, 7.89%
Insomnia (sleeplessness): 2 people, 5.26%
Blood Pressure Abnormal: 2 people, 5.26%
Breast Cancer Metastatic: 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Sertraline and have Increased upper airway secretion?

- Check whether Increased upper airway secretion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sertraline:

Sertraline (153,305 reports)

Browse all side effects of Sertraline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Increased upper airway secretion:

Increased upper airway secretion (616 drugs)

Browse all the conditions that are associated with Increased upper airway secretion:

Increased upper airway secretion (627 conditions)

Related publications that referenced our studies

Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on sertraline hydrochloride (the active ingredients of Sertraline) and Sertraline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.