Sertraline and Male sexual dysfunction - a phase IV clinical study of FDA data

Summary:

Male sexual dysfunction is reported as a side effect among people who take Sertraline (sertraline hydrochloride), especially for people who are 20-29 old, have been taking the drug for < 1 month also take Paracetamol, and have Obsessive-compulsive disorder.

The phase IV clinical study analyzes which people have Male sexual dysfunction when taking Sertraline. It is created by eHealthMe based on reports of 146,463 people who have side effects when taking Sertraline from the FDA, and is updated regularly.

What is Sertraline?

Sertraline has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 153,304 Sertraline users. Check the latest studies of Sertraline.

What is Male sexual dysfunction?

Male sexual dysfunction (impaired sexual function in male) is found to be associated with 50 drugs and 154 conditions by eHealthMe. Check the latest studies of Male sexual dysfunction.

On Jul, 27, 2026

146,463 people reported to have side effects when taking Sertraline.
Among them, 75 people (0.05%) have Male sexual dysfunction.

Could Sertraline cause Male sexual dysfunction?

Among these 75 people:

How long have people been on Sertraline when they have Male sexual dysfunction? *

What is the age of people who have Male sexual dysfunction when taking Sertraline? *

What are other drugs people take besides Sertraline? *

What are other side effects people have besides Male sexual dysfunction? *

Disturbance In Sexual Arousal: 18 people, 24.00%
Suicidal Ideation: 17 people, 22.67%
Intentional Self-Injury: 16 people, 21.33%
Libido Decreased (loss of interest in sex): 14 people, 18.67%
Loss Of Libido (loss of sexual urge): 14 people, 18.67%
Erection Problems: 9 people, 12.00%
Barrett's Oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach): 7 people, 9.33%
Withdrawal Syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 7 people, 9.33%
Orgasmic Dysfunction (not getting orgasm): 6 people, 8.00%
Genital Hypoaesthesia (sensation loss of genital): 5 people, 6.67%

What are the existing conditions these people have? *

Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 10 people, 13.33%
Sleep Disorder: 2 people, 2.67%
Bipolar Disorder (mood disorder): 1 person, 1.33%
Acne (skin problems that cause pimples): 1 person, 1.33%

* Approximation only. Some reports may have incomplete information.

Do you take Sertraline and have Male sexual dysfunction?

- Check whether Male sexual dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sertraline:

Sertraline (153,304 reports)

Browse all side effects of Sertraline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Male sexual dysfunction:

Male sexual dysfunction (50 drugs)

Browse all the conditions that are associated with Male sexual dysfunction:

Male sexual dysfunction (154 conditions)

Related publications that referenced our studies

Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on sertraline hydrochloride (the active ingredients of Sertraline) and Sertraline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.