Sertraline and Spasmodic dysphonia - a phase IV clinical study of FDA data

Summary:

Spasmodic dysphonia is reported as a side effect among people who take Sertraline (sertraline hydrochloride), especially for people who are male, 30-39 old, also take Haloperidol, and have Bipolar disorder.

The phase IV clinical study analyzes which people have Spasmodic dysphonia when taking Sertraline. It is created by eHealthMe based on reports of 146,463 people who have side effects when taking Sertraline from the FDA, and is updated regularly.

What is Sertraline?

Sertraline has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 153,308 Sertraline users. Check the latest studies of Sertraline.

What is Spasmodic dysphonia?

Spasmodic dysphonia (a voice disorder characterized by involuntary movements or spasms of one or more muscles of the larynx) is found to be associated with 50 drugs and 182 conditions by eHealthMe. Check the latest studies of Spasmodic dysphonia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

146,463 people reported to have side effects when taking Sertraline.
Among them, 13 people (0.01%) have Spasmodic dysphonia.

Could Sertraline cause Spasmodic dysphonia?

Among these 13 people:

What is the gender of people who have Spasmodic dysphonia when taking Sertraline? *

female: 9.09 %
male: 90.91 %

What is the age of people who have Spasmodic dysphonia when taking Sertraline? *

What are other drugs people take besides Sertraline? *

Amlodipine: 10 people, 76.92%
Omeprazole: 10 people, 76.92%
Loratadine: 10 people, 76.92%
Haloperidol: 10 people, 76.92%
Ceftriaxone: 6 people, 46.15%
Metronidazole: 6 people, 46.15%
Lorazepam: 5 people, 38.46%
Dexamethasone: 4 people, 30.77%
Piperacillin And Tazobactam: 2 people, 15.38%
Piperacillin: 2 people, 15.38%

What are other side effects people have besides Spasmodic dysphonia? *

Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 5 people, 38.46%
Drug Ineffective: 2 people, 15.38%
Weight Increased: 1 person, 7.69%
Fatigue (feeling of tiredness): 1 person, 7.69%
Itching: 1 person, 7.69%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 7.69%
Hyperhidrosis (abnormally increased sweating): 1 person, 7.69%
Hepatic Enzyme Increased: 1 person, 7.69%
Glycosylated Haemoglobin Increased: 1 person, 7.69%
Electrocardiogram T Wave Inversion: 1 person, 7.69%

What are the existing conditions these people have? *

Bipolar Disorder (mood disorder): 10 people, 76.92%
High Blood Pressure: 5 people, 38.46%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 38.46%
Oedema (fluid collection in tissue): 2 people, 15.38%
Suicidal Ideation: 1 person, 7.69%
Sepsis (a severe blood infection that can lead to organ failure and death): 1 person, 7.69%
Postpartum Depression (depression suffered by a mother following childbirth): 1 person, 7.69%
Post-Traumatic Stress Disorder: 1 person, 7.69%
On And Off Phenomenon: 1 person, 7.69%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Sertraline and have Spasmodic dysphonia?

- Check whether Spasmodic dysphonia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sertraline:

Sertraline (153,308 reports)

Browse all side effects of Sertraline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Spasmodic dysphonia:

Spasmodic dysphonia (50 drugs)

Browse all the conditions that are associated with Spasmodic dysphonia:

Spasmodic dysphonia (182 conditions)

Related publications that referenced our studies

Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on sertraline hydrochloride (the active ingredients of Sertraline) and Sertraline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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