Sertraline and Weight bearing difficulty - a phase IV clinical study of FDA data

Summary:

Weight bearing difficulty is reported as a side effect among people who take Sertraline (sertraline hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Methylprednisolone Sodium Succinate, and have Breast cancer.

The phase IV clinical study analyzes which people have Weight bearing difficulty when taking Sertraline. It is created by eHealthMe based on reports of 146,463 people who have side effects when taking Sertraline from the FDA, and is updated regularly.

What is Sertraline?

Sertraline has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 153,305 Sertraline users. Check the latest studies of Sertraline.

What is Weight bearing difficulty?

Weight bearing difficulty (difficulty due to weight of thigh fat deposition) is found to be associated with 330 drugs and 827 conditions by eHealthMe. Check the latest studies of Weight bearing difficulty.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 15, 2026

146,463 people reported to have side effects when taking Sertraline.
Among them, 26 people (0.02%) have Weight bearing difficulty.

Could Sertraline cause Weight bearing difficulty?

Among these 26 people:

How long have people been on Sertraline when they have Weight bearing difficulty? *

What is the gender of people who have Weight bearing difficulty when taking Sertraline? *

female: 84.21 %
male: 15.79 %

What is the age of people who have Weight bearing difficulty when taking Sertraline? *

What are other drugs people take besides Sertraline? *

Sulfasalazine: 8 people, 30.77%
Azathioprine: 8 people, 30.77%
Prednisone: 8 people, 30.77%
Benadryl: 8 people, 30.77%
Methotrexate: 8 people, 30.77%
Methylprednisolone Sodium Succinate: 8 people, 30.77%
Tylenol: 7 people, 26.92%
Acetaminophen: 4 people, 15.38%
Humira: 4 people, 15.38%
Aripiprazole: 3 people, 11.54%

What are other side effects people have besides Weight bearing difficulty? *

Back Pain: 13 people, 50.00%
Pain In Extremity: 12 people, 46.15%
Joint Pain: 12 people, 46.15%
Drug Ineffective: 11 people, 42.31%
Fatigue (feeling of tiredness): 11 people, 42.31%
Weakness: 10 people, 38.46%
Nausea (feeling of having an urge to vomit): 9 people, 34.62%
Tibia Fracture (fracture of lower leg bone): 9 people, 34.62%
Dry Eyes (lack of adequate tears): 9 people, 34.62%
Fall: 9 people, 34.62%

What are the existing conditions these people have? *

Breast Cancer: 8 people, 30.77%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 19.23%
Muscle Spasms (muscle contraction): 4 people, 15.38%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 11.54%
Post Concussion Syndrome: 3 people, 11.54%
Sleep Disorder: 3 people, 11.54%
Nausea (feeling of having an urge to vomit): 3 people, 11.54%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 7.69%
Uterine Haemorrhage (uterine bleeding): 2 people, 7.69%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Sertraline and have Weight bearing difficulty?

- Check whether Weight bearing difficulty is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sertraline:

Sertraline (153,305 reports)

Browse all side effects of Sertraline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weight bearing difficulty:

Weight bearing difficulty (330 drugs)

Browse all the conditions that are associated with Weight bearing difficulty:

Weight bearing difficulty (827 conditions)

Related publications that referenced our studies

Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on sertraline hydrochloride (the active ingredients of Sertraline) and Sertraline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.