Sildenafil citrate and Middle insomnia - a phase IV clinical study of FDA data

Summary:

Middle insomnia is reported as a side effect among people who take Sildenafil citrate (sildenafil citrate), especially for people who are female, 60+ old, also take Orenitram, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Middle insomnia when taking Sildenafil citrate. It is created by eHealthMe based on reports of 22,637 people who have side effects when taking Sildenafil citrate from the FDA, and is updated regularly.

What is Sildenafil citrate?

Sildenafil citrate has active ingredients of sildenafil citrate. It is often used in erection problems. eHealthMe is studying from 23,013 Sildenafil citrate users. Check the latest studies of Sildenafil citrate.

What is Middle insomnia?

Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night) is found to be associated with 988 drugs and 970 conditions by eHealthMe. Check the latest studies of Middle insomnia.

On Jul, 12, 2026

22,637 people reported to have side effects when taking Sildenafil citrate.
Among them, 12 people (0.05%) have Middle insomnia.

Could Sildenafil citrate cause Middle insomnia?

Among these 12 people:

What is the gender of people who have Middle insomnia when taking Sildenafil citrate? *

female: 58.33 %
male: 41.67 %

What is the age of people who have Middle insomnia when taking Sildenafil citrate? *

What are other drugs people take besides Sildenafil citrate? *

What are other side effects people have besides Middle insomnia? *

Hypotension (abnormally low blood pressure): 7 people, 58.33%
Weight Increased: 7 people, 58.33%
Headache (pain in head): 6 people, 50.00%
Nausea (feeling of having an urge to vomit): 5 people, 41.67%
Weight Decreased: 5 people, 41.67%
Oropharyngeal Pain: 4 people, 33.33%
Malaise (a feeling of general discomfort or uneasiness): 4 people, 33.33%
Joint Pain: 4 people, 33.33%
Diarrhea: 4 people, 33.33%
Pain In Jaw: 4 people, 33.33%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 50.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 25.00%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 3 people, 25.00%
Post-Traumatic Stress Disorder: 1 person, 8.33%
Pain: 1 person, 8.33%
Oedema Peripheral (superficial swelling): 1 person, 8.33%
Multiple Allergies (allergy to multiple agents): 1 person, 8.33%
Migraine (headache): 1 person, 8.33%
Faeces Hard: 1 person, 8.33%
Depression: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Sildenafil citrate and have Middle insomnia?

- Check whether Middle insomnia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sildenafil citrate:

Sildenafil citrate (23,013 reports)

Middle insomnia treatments and more:

Middle insomnia (21,952 reports)

Browse all side effects of Sildenafil citrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Middle insomnia:

Middle insomnia (988 drugs)

Browse all the conditions that are associated with Middle insomnia:

Middle insomnia (970 conditions)

Related publications that referenced our studies

Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .

How the study uses the data?

The study uses data from the FDA. It is based on sildenafil citrate (the active ingredients of Sildenafil citrate) and Sildenafil citrate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.