Sildenafil citrate and Muscle function loss - a phase IV clinical study of FDA data

Summary:

Muscle function loss is reported as a side effect among people who take Sildenafil citrate (sildenafil citrate), especially for people who are male, 50-59 old, also take Allopurinol, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Muscle function loss when taking Sildenafil citrate. It is created by eHealthMe based on reports of 22,637 people who have side effects when taking Sildenafil citrate from the FDA, and is updated regularly.

What is Sildenafil citrate?

Sildenafil citrate has active ingredients of sildenafil citrate. It is often used in erection problems. eHealthMe is studying from 23,013 Sildenafil citrate users. Check the latest studies of Sildenafil citrate.

What is Muscle function loss?

Muscle function loss is found to be associated with 1,000 drugs and 1,521 conditions by eHealthMe. Check the latest studies of Muscle function loss.



On Aug, 03, 2026

22,637 people reported to have side effects when taking Sildenafil citrate.
Among them, 11 people (0.05%) have Muscle function loss.

Could Sildenafil citrate cause Muscle function loss?

Among these 11 people:

What is the gender of people who have Muscle function loss when taking Sildenafil citrate? *

  • female: 36.36 %
  • male: 63.64 %

What is the age of people who have Muscle function loss when taking Sildenafil citrate? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 75 %
  • 60+: 25 %

What are other drugs people take besides Sildenafil citrate? *

  1. Irbesartan: 6 people, 54.55%
  2. Allopurinol: 6 people, 54.55%
  3. Simvastatin: 5 people, 45.45%
  4. Clarithromycin: 5 people, 45.45%
  5. Cyclosporine: 5 people, 45.45%
  6. Hydrocortisone: 1 person, 9.09%
  7. Adempas: 1 person, 9.09%
  8. Atenolol: 1 person, 9.09%
  9. Eliquis: 1 person, 9.09%
  10. Zocor: 1 person, 9.09%

What are other side effects people have besides Muscle function loss? *

  1. Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 6 people, 54.55%
  2. Myopathy (a muscular disease in which the muscle fibres do not function): 6 people, 54.55%
  3. Hyperkalemia (damage to or disease of the kidney): 6 people, 54.55%
  4. Blood Creatine Phosphokinase Increased: 6 people, 54.55%
  5. Fatigue (feeling of tiredness): 2 people, 18.18%
  6. Blood Luteinising Hormone Abnormal: 1 person, 9.09%
  7. Blood Prolactin Decreased: 1 person, 9.09%
  8. Blood Testosterone Decreased: 1 person, 9.09%
  9. Blood Follicle Stimulating Hormone Abnormal: 1 person, 9.09%
  10. Blood Thyroid Stimulating Hormone Abnormal: 1 person, 9.09%

What are the existing conditions these people have? *

  1. Respiratory Tract Infection: 6 people, 54.55%
  2. High Blood Cholesterol: 6 people, 54.55%
  3. Gout (uric acid crystals building up in the body): 3 people, 27.27%
  4. Blood Calcium Decreased: 3 people, 27.27%
  5. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 9.09%
  6. Osteoporosis (bones weak and more likely to break): 1 person, 9.09%
  7. Migraine (headache): 1 person, 9.09%
  8. High Blood Pressure: 1 person, 9.09%
  9. Blood Pressure Abnormal: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Sildenafil citrate and have Muscle function loss?

- Check whether Muscle function loss is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sildenafil citrate:

Muscle function loss treatments and more:

How severe was Muscle function loss and when was it recovered:

Expand to all the drugs that have ingredients of sildenafil citrate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sildenafil citrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle function loss:

Browse all the conditions that are associated with Muscle function loss:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on sildenafil citrate (the active ingredients of Sildenafil citrate) and Sildenafil citrate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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