Silodosin and Lactic acidosis - a phase IV clinical study of FDA data

Summary:

Lactic acidosis is reported as a side effect among people who take Silodosin (silodosin), especially for people who are male, 60+ old, also take Pantoprazole, and have High blood pressure.

The phase IV clinical study analyzes which people have Lactic acidosis when taking Silodosin. It is created by eHealthMe based on reports of 3,814 people who have side effects when taking Silodosin from the FDA, and is updated regularly.

What is Silodosin?

Silodosin has active ingredients of silodosin. eHealthMe is studying from 3,839 Silodosin users. Check the latest studies of Silodosin.

What is Lactic acidosis?

Lactic acidosis (low ph in body tissues) is found to be associated with 995 drugs and 1,281 conditions by eHealthMe. Check the latest studies of Lactic acidosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

3,814 people reported to have side effects when taking Silodosin.
Among them, 15 people (0.39%) have Lactic acidosis.

Among these 15 people:

What is the gender of people who have Lactic acidosis when taking Silodosin? *

female: 0.0 %
male: 100 %

What is the age of people who have Lactic acidosis when taking Silodosin? *

What are other drugs people take besides Silodosin? *

What are other side effects people have besides Lactic acidosis? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 13 people, 86.67%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 13 people, 86.67%
Hypoglycemia (low blood sugar): 13 people, 86.67%
Hyperkalemia (damage to or disease of the kidney): 2 people, 13.33%
Atrioventricular Block Complete (heart block complete): 2 people, 13.33%
Weakness: 1 person, 6.67%
Sopor (sleep): 1 person, 6.67%
Arrhythmias (irregular heartbeat): 1 person, 6.67%

What are the existing conditions these people have? *

High Blood Pressure: 15 people, 100.00%
Type 2 Diabetes: 14 people, 93.33%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 13 people, 86.67%
Enlarged Prostate: 13 people, 86.67%
Dyslipidaemia (abnormal amount of lipids): 13 people, 86.67%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 13.33%
Cardiac Disorder: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Silodosin and have Lactic acidosis?

- Check whether Lactic acidosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Silodosin:

Silodosin (3,839 reports)

Lactic acidosis treatments and more:

Lactic acidosis (34,314 reports)

Browse all side effects of Silodosin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lactic acidosis:

Lactic acidosis (995 drugs)

Browse all the conditions that are associated with Lactic acidosis:

Lactic acidosis (1,281 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on silodosin (the active ingredients of Silodosin) and Silodosin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.