Silodosin and Unilateral hydronephrosis - a phase IV clinical study of FDA data

Summary:

Unilateral hydronephrosis is reported as a side effect among people who take Silodosin (silodosin), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Allopurinol, and have Enlarged prostate.

The phase IV clinical study analyzes which people have Unilateral hydronephrosis when taking Silodosin. It is created by eHealthMe based on reports of 3,814 people who have side effects when taking Silodosin from the FDA, and is updated regularly.

What is Silodosin?

Silodosin has active ingredients of silodosin. eHealthMe is studying from 3,839 Silodosin users. Check the latest studies of Silodosin.

What is Unilateral hydronephrosis?

Unilateral hydronephrosis (kidney stone that causes obstruction of the ureter) is found to be associated with 1,009 drugs and 1,194 conditions by eHealthMe. Check the latest studies of Unilateral hydronephrosis.



On Jul, 27, 2026

3,814 people reported to have side effects when taking Silodosin.
Among them, 14 people (0.37%) have Unilateral hydronephrosis.

Could Silodosin cause Unilateral hydronephrosis?

Among these 14 people:

How long have people been on Silodosin when they have Unilateral hydronephrosis? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Unilateral hydronephrosis when taking Silodosin? *

  • female: 0.0 %
  • male: 100 %

What is the age of people who have Unilateral hydronephrosis when taking Silodosin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

What are other drugs people take besides Silodosin? *

  1. Allopurinol: 4 people, 28.57%
  2. Truvada: 3 people, 21.43%
  3. Norvir: 3 people, 21.43%
  4. Xanax: 2 people, 14.29%
  5. Niacin: 2 people, 14.29%
  6. Aspirin: 2 people, 14.29%
  7. Clarithromycin: 2 people, 14.29%
  8. Cordarone: 2 people, 14.29%
  9. Cortril: 2 people, 14.29%
  10. Dapagliflozin: 2 people, 14.29%

What are other side effects people have besides Unilateral hydronephrosis? *

  1. Acute Kidney Failure: 5 people, 35.71%
  2. Anaemia (lack of blood): 4 people, 28.57%
  3. Urination - Painful: 4 people, 28.57%
  4. Kidney Infection (Pyelonephritis): 4 people, 28.57%
  5. Oedema Peripheral (superficial swelling): 3 people, 21.43%
  6. Kidney Stones: 3 people, 21.43%
  7. Urinary Tract Infection: 3 people, 21.43%
  8. Urinary Retention (the inability to completely or partially empty the bladder): 3 people, 21.43%
  9. Hypoaesthesia (reduced sense of touch or sensation): 2 people, 14.29%
  10. Haemorrhage (bleeding): 2 people, 14.29%

What are the existing conditions these people have? *

  1. Enlarged Prostate: 9 people, 64.29%
  2. High Blood Pressure: 5 people, 35.71%
  3. Gout (uric acid crystals building up in the body): 4 people, 28.57%
  4. Urination - Painful: 3 people, 21.43%
  5. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 14.29%
  6. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 14.29%
  7. Diabetes: 2 people, 14.29%
  8. Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 2 people, 14.29%
  9. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 14.29%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Silodosin and have Unilateral hydronephrosis?

- Check whether Unilateral hydronephrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Silodosin:

Unilateral hydronephrosis treatments and more:

How severe was Unilateral hydronephrosis and when was it recovered:

Expand to all the drugs that have ingredients of silodosin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Silodosin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Unilateral hydronephrosis:

Browse all the conditions that are associated with Unilateral hydronephrosis:


How the study uses the data?

The study uses data from the FDA. It is based on silodosin (the active ingredients of Silodosin) and Silodosin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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