Silvadene and Chills - a phase IV clinical study of FDA data

Summary:

Chills is reported as a side effect among people who take Silvadene (silver sulfadiazine), especially for people who are female, 30-39 old, also take Vancomycin, and have Breast cancer.

The phase IV clinical study analyzes which people have Chills when taking Silvadene. It is created by eHealthMe based on reports of 1,154 people who have side effects when taking Silvadene from the FDA, and is updated regularly.

What is Silvadene?

Silvadene has active ingredients of silver sulfadiazine. eHealthMe is studying from 1,161 Silvadene users. Check the latest studies of Silvadene.

What is Chills?

Chills (felling of cold) is found to be associated with 2,551 drugs and 3,475 conditions by eHealthMe. Check the latest studies of Chills.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Jul, 28, 2026

1,154 people reported to have side effects when taking Silvadene.
Among them, 24 people (2.08%) have Chills.

Could Silvadene cause Chills?

Among these 24 people:

What is the gender of people who have Chills when taking Silvadene? *

  • female: 73.91 %
  • male: 26.09 %

What is the age of people who have Chills when taking Silvadene? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 54.55 %
  • 40-49: 13.64 %
  • 50-59: 9.09 %
  • 60+: 22.73 %

What are other drugs people take besides Silvadene? *

  1. Vancomycin: 14 people, 58.33%
  2. Vicodin: 13 people, 54.17%
  3. Zofran: 13 people, 54.17%
  4. Augmentin '125': 13 people, 54.17%
  5. Ativan: 13 people, 54.17%
  6. Flagyl: 13 people, 54.17%
  7. Klonopin: 12 people, 50.00%
  8. Paxil: 12 people, 50.00%
  9. Ritalin: 12 people, 50.00%
  10. Clonazepam: 12 people, 50.00%

What are other side effects people have besides Chills? *

  1. Nausea (feeling of having an urge to vomit): 17 people, 70.83%
  2. Weakness: 16 people, 66.67%
  3. Fatigue (feeling of tiredness): 15 people, 62.50%
  4. Headache (pain in head): 15 people, 62.50%
  5. Dyspnea (difficult or laboured breathing): 14 people, 58.33%
  6. Sepsis (a severe blood infection that can lead to organ failure and death): 14 people, 58.33%
  7. Unresponsive To Stimuli: 13 people, 54.17%
  8. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 13 people, 54.17%
  9. Rashes (redness): 13 people, 54.17%
  10. Chest Pain: 13 people, 54.17%

What are the existing conditions these people have? *

  1. Breast Cancer: 10 people, 41.67%
  2. Pain: 3 people, 12.50%
  3. Diabetes: 3 people, 12.50%
  4. Immune System Disorder: 2 people, 8.33%
  5. High Blood Pressure: 2 people, 8.33%
  6. Renal Disorder (kidney disease): 2 people, 8.33%
  7. Pressure Ulcer: 2 people, 8.33%
  8. Neuralgia (pain in one or more nerves): 2 people, 8.33%
  9. Cardiac Disorder: 2 people, 8.33%
  10. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Silvadene and have Chills?

- Check whether Chills is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Silvadene:

Chills treatments and more:

How severe was Chills and when was it recovered:

Expand to all the drugs that have ingredients of silver sulfadiazine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Silvadene:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chills:

Browse all the conditions that are associated with Chills:


How the study uses the data?

The study uses data from the FDA. It is based on silver sulfadiazine (the active ingredients of Silvadene) and Silvadene (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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