Simbrinza and Sinusitis - a phase IV clinical study of FDA data

Summary:

Sinusitis is reported as a side effect among people who take Simbrinza (brimonidine tartrate; brinzolamide), especially for people who are female, 60+ old, also take Epinephrine, and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people have Sinusitis when taking Simbrinza. It is created by eHealthMe based on reports of 4,527 people who have side effects when taking Simbrinza from the FDA, and is updated regularly.

What is Simbrinza?

Simbrinza has active ingredients of brimonidine tartrate; brinzolamide. It is often used in glaucoma. eHealthMe is studying from 4,543 Simbrinza users. Check the latest studies of Simbrinza.

What is Sinusitis?

Sinusitis (inflammation of sinus) is found to be associated with 2,399 drugs and 2,727 conditions by eHealthMe. Check the latest studies of Sinusitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

4,527 people reported to have side effects when taking Simbrinza.
Among them, 30 people (0.66%) have Sinusitis.

Among these 30 people:

What is the gender of people who have Sinusitis when taking Simbrinza? *

female: 92.59 %
male: 7.41 %

What is the age of people who have Sinusitis when taking Simbrinza? *

What are other drugs people take besides Simbrinza? *

What are other side effects people have besides Sinusitis? *

Cataract (clouding of the lens inside the eye): 7 people, 23.33%
Dizziness: 7 people, 23.33%
Cough: 5 people, 16.67%
Cardiac Disorder: 5 people, 16.67%
Small Intestinal Obstruction (blockage in small intestine): 5 people, 16.67%
Hypotension (abnormally low blood pressure): 5 people, 16.67%
Oropharyngeal Pain: 5 people, 16.67%
Ocular Hypertension (intraocular pressure higher than normal): 5 people, 16.67%
Nasopharyngitis (inflammation of the nasopharynx): 5 people, 16.67%
Weight Decreased: 5 people, 16.67%

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 17 people, 56.67%
Asthma: 6 people, 20.00%
Primary Immunodeficiency Syndrome: 3 people, 10.00%
High Blood Cholesterol: 3 people, 10.00%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 3 people, 10.00%
High Blood Pressure: 2 people, 6.67%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 3.33%
Peripheral Swelling: 1 person, 3.33%
Nervousness: 1 person, 3.33%
Myopathy (a muscular disease in which the muscle fibres do not function): 1 person, 3.33%

* Approximation only. Some reports may have incomplete information.

Do you take Simbrinza and have Sinusitis?

- Check whether Sinusitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simbrinza:

Simbrinza (4,543 reports)

Sinusitis treatments and more:

Sinusitis (153,485 reports)

How severe was Sinusitis and when was it recovered:

Sinusitis in Simbrinza

Expand to all the drugs that have ingredients of brimonidine tartrate; brinzolamide:

Sinusitis and drugs with ingredients of brimonidine tartrate; brinzolamide (7 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Simbrinza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinusitis:

Sinusitis (2,399 drugs)

Browse all the conditions that are associated with Sinusitis:

Sinusitis (2,727 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on brimonidine tartrate; brinzolamide (the active ingredients of Simbrinza) and Simbrinza (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.