Simcor and Formication - a phase IV clinical study of FDA data

Summary:

Formication is reported as a side effect among people who take Simcor (niacin; simvastatin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Aspirin, and have Low density lipoprotein increased.

The phase IV clinical study analyzes which people have Formication when taking Simcor. It is created by eHealthMe based on reports of 11,438 people who have side effects when taking Simcor from the FDA, and is updated regularly.

What is Simcor?

Simcor has active ingredients of niacin; simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 11,604 Simcor users. Check the latest studies of Simcor.

What is Formication?

Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin) is found to be associated with 557 drugs and 917 conditions by eHealthMe. Check the latest studies of Formication.

On Apr, 17, 2026

11,438 people reported to have side effects when taking Simcor.
Among them, 38 people (0.33%) have Formication.

Among these 38 people:

How long have people been on Simcor when they have Formication? *

What is the gender of people who have Formication when taking Simcor? *

female: 35.14 %
male: 64.86 %

What is the age of people who have Formication when taking Simcor? *

What are other drugs people take besides Simcor? *

What are other side effects people have besides Formication? *

Skin Blushing/flushing (a sudden reddening of the face, neck): 21 people, 55.26%
Itching: 12 people, 31.58%
Feeling Hot: 11 people, 28.95%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 6 people, 15.79%
Rashes (redness): 6 people, 15.79%
Skin Burning Sensation: 4 people, 10.53%
Hot Flush (sudden feelings of heat): 3 people, 7.89%
Generalised Erythema (redness of the skin all over the body): 3 people, 7.89%
Hyperhidrosis (abnormally increased sweating): 2 people, 5.26%
Insomnia (sleeplessness): 2 people, 5.26%

What are the existing conditions these people have? *

Low Density Lipoprotein Increased (cholesterol increased in blood): 8 people, 21.05%
High Density Lipoprotein Decreased: 6 people, 15.79%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 5.26%
High Blood Pressure: 2 people, 5.26%
Glaucoma (increased fluid pressure in the eye with vision loss): 2 people, 5.26%
Skin Blushing/flushing (a sudden reddening of the face, neck): 1 person, 2.63%
Heart Attack: 1 person, 2.63%
Enlarged Prostate: 1 person, 2.63%
Diabetes: 1 person, 2.63%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 1 person, 2.63%

* Approximation only. Some reports may have incomplete information.

Do you take Simcor and have Formication?

- Check whether Formication is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simcor:

Simcor (11,604 reports)

Formication treatments and more:

Formication (8,246 reports)

Browse all side effects of Simcor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Formication:

Formication (557 drugs)

Browse all the conditions that are associated with Formication:

Formication (917 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on niacin; simvastatin (the active ingredients of Simcor) and Simcor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.