Simcor and Hypotension - a phase IV clinical study of FDA data
Summary:
Hypotension is reported as a side effect among people who take Simcor (niacin; simvastatin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Lisinopril, and have High blood pressure.
The phase IV clinical study analyzes which people have Hypotension when taking Simcor. It is created by eHealthMe based on reports of 11,438 people who have side effects when taking Simcor from the FDA, and is updated regularly.
What is Simcor?
Simcor has active ingredients of niacin; simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 11,604 Simcor users. Check the latest studies of Simcor.
What is Hypotension?
Hypotension (abnormally low blood pressure) is found to be associated with 3,359 drugs and 4,756 conditions by eHealthMe. Check the latest studies of Hypotension.
11,438 people reported to have side effects when taking Simcor.
Among them, 45 people (0.39%) have Hypotension.

Among these 45 people:
How long have people been on Simcor when they have Hypotension? *
- < 1 month: 66.67 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 11.11 %
- 1 - 2 years: 22.22 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Hypotension when taking Simcor? *
- female: 29.27 %
- male: 70.73 %
What is the age of people who have Hypotension when taking Simcor? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 3.57 %
- 40-49: 14.29 %
- 50-59: 25.0 %
- 60+: 57.14 %
What are other drugs people take besides Simcor? *
- Lisinopril: 7 people, 15.56%
- Aspirin: 6 people, 13.33%
- Benicar: 5 people, 11.11%
- Fish Oil: 5 people, 11.11%
- Zolpidem: 4 people, 8.89%
- Neurontin: 4 people, 8.89%
- Benicar Hct: 4 people, 8.89%
- Synthroid: 4 people, 8.89%
- Bystolic: 3 people, 6.67%
- Xanax: 3 people, 6.67%
What are other side effects people have besides Hypotension? *
- Dizziness: 15 people, 33.33%
- Skin Blushing/flushing (a sudden reddening of the face, neck): 14 people, 31.11%
- Weakness: 7 people, 15.56%
- Rashes (redness): 7 people, 15.56%
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 6 people, 13.33%
- Dehydration (dryness resulting from the removal of water): 5 people, 11.11%
- Fainting (loss of consciousness and postural tone): 5 people, 11.11%
- Fatigue (feeling of tiredness): 5 people, 11.11%
- Head Injury: 5 people, 11.11%
- Malaise (a feeling of general discomfort or uneasiness): 4 people, 8.89%
What are the existing conditions these people have? *
- High Blood Pressure: 7 people, 15.56%
- Insomnia (sleeplessness): 5 people, 11.11%
- High Density Lipoprotein Decreased: 5 people, 11.11%
- Low Density Lipoprotein Increased (cholesterol increased in blood): 4 people, 8.89%
- Dyslipidaemia (abnormal amount of lipids): 2 people, 4.44%
- Breast Cancer: 2 people, 4.44%
- Joint Pain: 2 people, 4.44%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 4.44%
- Prostate Cancer: 2 people, 4.44%
- Renal Disorder (kidney disease): 1 person, 2.22%
* Approximation only. Some reports may have incomplete information.
Do you take Simcor and have Hypotension?
- Check whether Hypotension is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Simcor:
- Simcor (11,604 reports)
Hypotension treatments and more:
- Hypotension (329,856 reports)
How severe was Hypotension and when was it recovered:
Expand to all the drugs that have ingredients of niacin; simvastatin:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Simcor:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Hypotension:
- Hypotension (3,359 drugs)
Browse all the conditions that are associated with Hypotension:
- Hypotension (4,756 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on niacin; simvastatin (the active ingredients of Simcor) and Simcor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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