Simethicone and Weight fluctuation - a phase IV clinical study of FDA data

Summary:

Weight fluctuation is reported as a side effect among people who take Simethicone (simethicone), especially for people who are female, 60+ old, also take Ciprodex, and have Short-bowel syndrome.

The phase IV clinical study analyzes which people have Weight fluctuation when taking Simethicone. It is created by eHealthMe based on reports of 6,434 people who have side effects when taking Simethicone from the FDA, and is updated regularly.

What is Simethicone?

Simethicone has active ingredients of simethicone. It is often used in gas. eHealthMe is studying from 6,763 Simethicone users. Check the latest studies of Simethicone.

What is Weight fluctuation?

Weight fluctuation is found to be associated with 897 drugs and 1,030 conditions by eHealthMe. Check the latest studies of Weight fluctuation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

6,434 people reported to have side effects when taking Simethicone.
Among them, 14 people (0.22%) have Weight fluctuation.

Could Simethicone cause Weight fluctuation?

Among these 14 people:

What is the gender of people who have Weight fluctuation when taking Simethicone? *

female: 64.29 %
male: 35.71 %

What is the age of people who have Weight fluctuation when taking Simethicone? *

What are other drugs people take besides Simethicone? *

What are other side effects people have besides Weight fluctuation? *

Skin Atrophy (wasting of skin): 6 people, 42.86%
Injection Site Irritation: 4 people, 28.57%
Injection Site Erythema (redness at injection site): 4 people, 28.57%
Overgrowth Bacterial (extra growth due to bacteria): 4 people, 28.57%
Appetite Disorder (abnormal eating habits): 4 people, 28.57%
Skin Reaction: 4 people, 28.57%
Gallbladder Disorder: 4 people, 28.57%
Fatigue (feeling of tiredness): 3 people, 21.43%
Joint Pain: 3 people, 21.43%
Migraine (headache): 3 people, 21.43%

What are the existing conditions these people have? *

Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 5 people, 35.71%
Flatulence (flatus expelled through the anus): 3 people, 21.43%
Immunodeficiency Common Variable: 3 people, 21.43%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 3 people, 21.43%
Itching: 2 people, 14.29%
Joint Pain: 2 people, 14.29%
Breast Cancer Metastatic: 2 people, 14.29%
Diarrhea: 2 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 14.29%
Hair Loss: 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Simethicone and have Weight fluctuation?

- Check whether Weight fluctuation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simethicone:

Simethicone (6,763 reports)

Browse all side effects of Simethicone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weight fluctuation:

Weight fluctuation (897 drugs)

Browse all the conditions that are associated with Weight fluctuation:

Weight fluctuation (1,030 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on simethicone (the active ingredients of Simethicone) and Simethicone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.