Simulect and Depression - a phase IV clinical study of FDA data

Summary:

Depression is reported as a side effect among people who take Simulect (basiliximab), especially for people who are male, 10-19 old, have been taking the drug for < 1 month also take Cellcept, and have Immunodeficiency disorders.

The phase IV clinical study analyzes which people have Depression when taking Simulect. It is created by eHealthMe based on reports of 3,859 people who have side effects when taking Simulect from the FDA, and is updated regularly.

What is Simulect?

Simulect has active ingredients of basiliximab. eHealthMe is studying from 3,861 Simulect users. Check the latest studies of Simulect.

What is Depression?

Depression is found to be associated with 3,208 drugs and 4,072 conditions by eHealthMe. Check the latest studies of Depression.



On Dec, 28, 2025

3,859 people reported to have side effects when taking Simulect.
Among them, 13 people (0.34%) have Depression.

Could Simulect cause Depression?

Among these 13 people:

How long have people been on Simulect when they have Depression? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Depression when taking Simulect? *

  • female: 25 %
  • male: 75 %

What is the age of people who have Depression when taking Simulect? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 54.55 %
  • 20-29: 9.09 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 36.36 %

What are other drugs people take besides Simulect? *

  1. Cellcept: 11 people, 84.62%
  2. Prograf: 8 people, 61.54%
  3. Accutane: 4 people, 30.77%
  4. Ovcon-35: 3 people, 23.08%
  5. Flolan: 3 people, 23.08%
  6. Solu-Medrol: 3 people, 23.08%
  7. Neoral: 3 people, 23.08%
  8. Valcyte: 3 people, 23.08%
  9. Prozac: 3 people, 23.08%
  10. Renagel: 2 people, 15.38%

What are other side effects people have besides Depression? *

  1. Acute Kidney Failure: 5 people, 38.46%
  2. High Blood Cholesterol: 4 people, 30.77%
  3. Tremor (trembling or shaking movements in one or more parts of your body): 4 people, 30.77%
  4. Blood Creatinine Increased: 4 people, 30.77%
  5. Gastroenteritis Viral (inflammation of stomach and intestine caused by virus infection): 3 people, 23.08%
  6. Lung Transplant Rejection (failure of lung transplant): 3 people, 23.08%
  7. Lung Infection: 3 people, 23.08%
  8. Intussusception: 3 people, 23.08%
  9. Headache (pain in head): 3 people, 23.08%
  10. Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 3 people, 23.08%

What are the existing conditions these people have? *

  1. Immunodeficiency Disorders: 3 people, 23.08%
  2. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1 person, 7.69%
  3. Acne Cystic (skin problems that cause pimples): 1 person, 7.69%
  4. Acne (skin problems that cause pimples): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Simulect and have Depression?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simulect:

Depression treatments and more:

How severe was Depression and when was it recovered:

Expand to all the drugs that have ingredients of basiliximab:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Simulect:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Depression:

Browse all the conditions that are associated with Depression:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on basiliximab (the active ingredients of Simulect) and Simulect (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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