Simulect and Hepatic failure - a phase IV clinical study of FDA data

Summary:

Hepatic failure is reported as a side effect among people who take Simulect (basiliximab), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Cellcept, and have Immunodeficiency disorders.

The phase IV clinical study analyzes which people have Hepatic failure when taking Simulect. It is created by eHealthMe based on reports of 3,859 people who have side effects when taking Simulect from the FDA, and is updated regularly.

What is Simulect?

Simulect has active ingredients of basiliximab. eHealthMe is studying from 3,861 Simulect users. Check the latest studies of Simulect.

What is Hepatic failure?

Hepatic failure (liver failure) is found to be associated with 1,542 drugs and 1,891 conditions by eHealthMe. Check the latest studies of Hepatic failure.



On Jul, 05, 2026

3,859 people reported to have side effects when taking Simulect.
Among them, 44 people (1.14%) have Hepatic failure.

Could Simulect cause Hepatic failure?

Among these 44 people:

How long have people been on Simulect when they have Hepatic failure? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hepatic failure when taking Simulect? *

  • female: 52.38 %
  • male: 47.62 %

What is the age of people who have Hepatic failure when taking Simulect? *

  • 0-1: 4.76 %
  • 2-9: 7.14 %
  • 10-19: 2.38 %
  • 20-29: 7.14 %
  • 30-39: 2.38 %
  • 40-49: 11.9 %
  • 50-59: 28.57 %
  • 60+: 35.71 %

What are other drugs people take besides Simulect? *

  1. Cellcept: 16 people, 36.36%
  2. Neoral: 15 people, 34.09%
  3. Prograf: 12 people, 27.27%
  4. Tacrolimus: 8 people, 18.18%
  5. Mycophenolate Mofetil: 6 people, 13.64%
  6. Urso 250: 4 people, 9.09%
  7. Lasix: 4 people, 9.09%
  8. Medrol: 4 people, 9.09%
  9. Cyclosporine: 4 people, 9.09%
  10. Methylprednisolone: 4 people, 9.09%

What are other side effects people have besides Hepatic failure? *

  1. Acute Kidney Failure: 18 people, 40.91%
  2. Hepatitis C: 11 people, 25.00%
  3. Liver Transplant Rejection (failure of liver transplant): 9 people, 20.45%
  4. Hepatic Enzyme Increased: 8 people, 18.18%
  5. Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 8 people, 18.18%
  6. Cholestasis (a condition where bile cannot flow from the liver to the duodenum): 8 people, 18.18%
  7. General Physical Health Deterioration (weak health status): 8 people, 18.18%
  8. Ascites (accumulation of fluid in the abdominal cavity): 7 people, 15.91%
  9. Kidney Transplant Rejection: 7 people, 15.91%
  10. Sepsis (a severe blood infection that can lead to organ failure and death): 6 people, 13.64%

What are the existing conditions these people have? *

  1. Immunodeficiency Disorders: 5 people, 11.36%
  2. Liver Transplant Rejection (failure of liver transplant): 2 people, 4.55%
  3. Urinary Tract Infection: 1 person, 2.27%
  4. Fever: 1 person, 2.27%
  5. Anaemia (lack of blood): 1 person, 2.27%
  6. Anaesthesia: 1 person, 2.27%
  7. Bacteraemia (presence of bacteria in the blood): 1 person, 2.27%
  8. Bacterial Infection: 1 person, 2.27%
  9. Bone Marrow Conditioning Regimen: 1 person, 2.27%
  10. Cholangitis Sclerosing (infection and obstruction of bile duct): 1 person, 2.27%

* Approximation only. Some reports may have incomplete information.

Do you take Simulect and have Hepatic failure?

- Check whether Hepatic failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simulect:

Hepatic failure treatments and more:

How severe was Hepatic failure and when was it recovered:

Expand to all the drugs that have ingredients of basiliximab:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Simulect:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatic failure:

Browse all the conditions that are associated with Hepatic failure:


How the study uses the data?

The study uses data from the FDA. It is based on basiliximab (the active ingredients of Simulect) and Simulect (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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