Sinemet cr and Arthritis - a phase IV clinical study of FDA data

Summary:

Arthritis is reported as a side effect among people who take Sinemet cr (carbidopa; levodopa), especially for people who are female, 60+ old, also take Magnesium, and have Muscle spasms.

The phase IV clinical study analyzes which people have Arthritis when taking Sinemet cr. It is created by eHealthMe based on reports of 2,682 people who have side effects when taking Sinemet cr from the FDA, and is updated regularly.

What is Sinemet cr?

Sinemet cr has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 2,852 Sinemet cr users. Check the latest studies of Sinemet cr.

What is Arthritis?

Arthritis (form of joint disorder that involves inflammation of one or more joints) is found to be associated with 1,964 drugs and 2,259 conditions by eHealthMe. Check the latest studies of Arthritis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

2,682 people reported to have side effects when taking Sinemet cr.
Among them, 15 people (0.56%) have Arthritis.

Among these 15 people:

What is the gender of people who have Arthritis when taking Sinemet cr? *

female: 71.43 %
male: 28.57 %

What is the age of people who have Arthritis when taking Sinemet cr? *

What are other drugs people take besides Sinemet cr? *

What are other side effects people have besides Arthritis? *

Fatigue (feeling of tiredness): 10 people, 66.67%
Weight Increased: 9 people, 60.00%
Dyskinesia (abnormality or impairment of voluntary movement): 9 people, 60.00%
Pain In Extremity: 9 people, 60.00%
On And Off Phenomenon: 9 people, 60.00%
Diarrhea: 8 people, 53.33%
Freezing Phenomenon: 8 people, 53.33%
Infection: 8 people, 53.33%
Dizziness: 7 people, 46.67%
Gait Disturbance: 7 people, 46.67%

What are the existing conditions these people have? *

Muscle Spasms (muscle contraction): 8 people, 53.33%
High Blood Pressure: 2 people, 13.33%
High Blood Cholesterol: 2 people, 13.33%
Type 2 Diabetes: 1 person, 6.67%
Back Pain: 1 person, 6.67%
Diabetes: 1 person, 6.67%
Diarrhea: 1 person, 6.67%
Flatulence (flatus expelled through the anus): 1 person, 6.67%
Folliculitis (infection of hair root): 1 person, 6.67%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Sinemet cr and have Arthritis?

- Check whether Arthritis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sinemet cr:

Sinemet cr (2,852 reports)

Arthritis treatments and more:

Arthritis (188,669 reports)

Browse all side effects of Sinemet cr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Arthritis:

Arthritis (1,964 drugs)

Browse all the conditions that are associated with Arthritis:

Arthritis (2,259 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on carbidopa; levodopa (the active ingredients of Sinemet cr) and Sinemet cr (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.