Sinemet cr and Terminal insomnia - a phase IV clinical study of FDA data

Summary:

Terminal insomnia is reported as a side effect among people who take Sinemet cr (carbidopa; levodopa), especially for people who are female, 60+ old, also take Neupro, and have Muscle spasms.

The phase IV clinical study analyzes which people have Terminal insomnia when taking Sinemet cr. It is created by eHealthMe based on reports of 2,682 people who have side effects when taking Sinemet cr from the FDA, and is updated regularly.

What is Sinemet cr?

Sinemet cr has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 2,852 Sinemet cr users. Check the latest studies of Sinemet cr.

What is Terminal insomnia?

Terminal insomnia (a sleep disorder in which there is an inability to fall asleep or to stay asleep as long as desired) is found to be associated with 203 drugs and 345 conditions by eHealthMe. Check the latest studies of Terminal insomnia.

On Jul, 18, 2026

2,682 people reported to have side effects when taking Sinemet cr.
Among them, 12 people (0.45%) have Terminal insomnia.

Could Sinemet cr cause Terminal insomnia?

Among these 12 people:

What is the gender of people who have Terminal insomnia when taking Sinemet cr? *

female: 75 %
male: 25 %

What is the age of people who have Terminal insomnia when taking Sinemet cr? *

What are other drugs people take besides Sinemet cr? *

What are other side effects people have besides Terminal insomnia? *

On And Off Phenomenon: 10 people, 83.33%
Urinary Tract Infection: 10 people, 83.33%
Dyskinesia (abnormality or impairment of voluntary movement): 10 people, 83.33%
Bradykinesia (decreased bodily movement. it is associated with basal ganglia diseases): 10 people, 83.33%
Muscle Spasms (muscle contraction): 10 people, 83.33%
Initial Insomnia (feeling of inadequate or poor-quality sleep): 10 people, 83.33%
Freezing Phenomenon: 10 people, 83.33%
Incontinence (lack of moderation or self-control): 9 people, 75.00%
Infection: 9 people, 75.00%
Diarrhea: 9 people, 75.00%

What are the existing conditions these people have? *

Muscle Spasms (muscle contraction): 8 people, 66.67%
Depression: 2 people, 16.67%
Stress And Anxiety: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Sinemet cr and have Terminal insomnia?

- Check whether Terminal insomnia is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sinemet cr:

Sinemet cr (2,852 reports)

Browse all side effects of Sinemet cr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Terminal insomnia:

Terminal insomnia (204 drugs)

Browse all the conditions that are associated with Terminal insomnia:

Terminal insomnia (345 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on carbidopa; levodopa (the active ingredients of Sinemet cr) and Sinemet cr (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.