Sinemet and Eyelid twitch - a phase IV clinical study of FDA data

Summary:

Eyelid twitch is reported as a side effect among people who take Sinemet (carbidopa; levodopa), especially for people who are male, 60+ old, also take Requip, and have Agitation.

The phase IV clinical study analyzes which people have Eyelid twitch when taking Sinemet. It is created by eHealthMe based on reports of 28,351 people who have side effects when taking Sinemet from the FDA, and is updated regularly.

What is Sinemet?

Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,601 Sinemet users. Check the latest studies of Sinemet.

What is Eyelid twitch?

Eyelid twitch (spontaneous and uncontrolled spasms of the muscles) is found to be associated with 528 drugs and 960 conditions by eHealthMe. Check the latest studies of Eyelid twitch.

On Jul, 16, 2026

28,351 people reported to have side effects when taking Sinemet.
Among them, 21 people (0.07%) have Eyelid twitch.

Among these 21 people:

What is the gender of people who have Eyelid twitch when taking Sinemet? *

female: 40 %
male: 60 %

What is the age of people who have Eyelid twitch when taking Sinemet? *

What are other drugs people take besides Sinemet? *

What are other side effects people have besides Eyelid twitch? *

Muscle Twitching: 4 people, 19.05%
Tremor (trembling or shaking movements in one or more parts of your body): 3 people, 14.29%
Agitation (state of anxiety or nervous excitement): 3 people, 14.29%
Oedema Lower Limb (fluid collection in tissue of lower leg): 3 people, 14.29%
Wheezing (a high-pitched whistling sound made while you breath): 2 people, 9.52%
Drowsiness: 2 people, 9.52%
Dyskinesia (abnormality or impairment of voluntary movement): 2 people, 9.52%
Dyspnea (difficult or laboured breathing): 2 people, 9.52%
Nausea (feeling of having an urge to vomit): 2 people, 9.52%
Memory Loss: 2 people, 9.52%

What are the existing conditions these people have? *

Stress And Anxiety: 1 person, 4.76%
Nausea (feeling of having an urge to vomit): 1 person, 4.76%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 4.76%
Multiple Myeloma (cancer of the plasma cells): 1 person, 4.76%
Juvenile Arthritis (arthritis-related condition that develops in children or teenagers): 1 person, 4.76%
Gastritis (inflammation of stomach): 1 person, 4.76%
Drooling (drop saliva uncontrollably from the mouth): 1 person, 4.76%
Depression: 1 person, 4.76%
Agitation (state of anxiety or nervous excitement): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Sinemet and have Eyelid twitch?

- Check whether Eyelid twitch is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sinemet:

Sinemet (29,601 reports)

Eyelid twitch treatments and more:

Eyelid twitch (7,214 reports)

Browse all side effects of Sinemet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Eyelid twitch:

Eyelid twitch (528 drugs)

Browse all the conditions that are associated with Eyelid twitch:

Eyelid twitch (960 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on carbidopa; levodopa (the active ingredients of Sinemet) and Sinemet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.