Sinemet and Hyperventilation - a phase IV clinical study of FDA data

Summary:

Hyperventilation is reported as a side effect among people who take Sinemet (carbidopa; levodopa), especially for people who are male, 60+ old, also take Stalevo 100, and have Hallucinations.

The phase IV clinical study analyzes which people have Hyperventilation when taking Sinemet. It is created by eHealthMe based on reports of 28,351 people who have side effects when taking Sinemet from the FDA, and is updated regularly.

What is Sinemet?

Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,600 Sinemet users. Check the latest studies of Sinemet.

What is Hyperventilation?

Hyperventilation is found to be associated with 736 drugs and 1,442 conditions by eHealthMe. Check the latest studies of Hyperventilation.

On Mar, 29, 2026

28,351 people reported to have side effects when taking Sinemet.
Among them, 41 people (0.14%) have Hyperventilation.

Among these 41 people:

What is the gender of people who have Hyperventilation when taking Sinemet? *

female: 30 %
male: 70 %

What is the age of people who have Hyperventilation when taking Sinemet? *

What are other drugs people take besides Sinemet? *

What are other side effects people have besides Hyperventilation? *

Stress And Anxiety: 16 people, 39.02%
Dyspnea (difficult or laboured breathing): 15 people, 36.59%
Hyperhidrosis (abnormally increased sweating): 13 people, 31.71%
Agitation (state of anxiety or nervous excitement): 12 people, 29.27%
On And Off Phenomenon: 11 people, 26.83%
Dyskinesia (abnormality or impairment of voluntary movement): 11 people, 26.83%
Gait Disturbance: 9 people, 21.95%
Fear: 9 people, 21.95%
Drug Ineffective: 9 people, 21.95%
Muscle Rigidity (muscle stiffness): 9 people, 21.95%

What are the existing conditions these people have? *

Depression: 3 people, 7.32%
Hallucinations (sensations that appear real but are created by your mind): 3 people, 7.32%
Abnormal Faeces (abnormal stool): 2 people, 4.88%
High Blood Cholesterol: 2 people, 4.88%
Stress And Anxiety: 2 people, 4.88%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 4.88%
Gastritis (inflammation of stomach): 2 people, 4.88%
Dyskinesia (abnormality or impairment of voluntary movement): 1 person, 2.44%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 2.44%
Delusion (a false belief or opinion): 1 person, 2.44%

* Approximation only. Some reports may have incomplete information.

Do you take Sinemet and have Hyperventilation?

- Check whether Hyperventilation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sinemet:

Sinemet (29,600 reports)

Browse all side effects of Sinemet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperventilation:

Hyperventilation (736 drugs)

Browse all the conditions that are associated with Hyperventilation:

Hyperventilation (1,442 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on carbidopa; levodopa (the active ingredients of Sinemet) and Sinemet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.