Sinemet and Purpura - a phase IV clinical study of FDA data

Summary:

Purpura is reported as a side effect among people who take Sinemet (carbidopa; levodopa), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Neurontin, and have Pain.

The phase IV clinical study analyzes which people have Purpura when taking Sinemet. It is created by eHealthMe based on reports of 28,351 people who have side effects when taking Sinemet from the FDA, and is updated regularly.

What is Sinemet?

Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,601 Sinemet users. Check the latest studies of Sinemet.

What is Purpura?

Purpura (purplish discoloration of the skin) is found to be associated with 941 drugs and 1,515 conditions by eHealthMe. Check the latest studies of Purpura.

On Jul, 19, 2026

28,351 people reported to have side effects when taking Sinemet.
Among them, 30 people (0.11%) have Purpura.

Among these 30 people:

How long have people been on Sinemet when they have Purpura? *

What is the gender of people who have Purpura when taking Sinemet? *

female: 46.67 %
male: 53.33 %

What is the age of people who have Purpura when taking Sinemet? *

What are other drugs people take besides Sinemet? *

What are other side effects people have besides Purpura? *

Rashes (redness): 10 people, 33.33%
Oedema Peripheral (superficial swelling): 7 people, 23.33%
Rash Macular (small, flat red spots): 7 people, 23.33%
Itching: 7 people, 23.33%
Thrombocytopenia (decrease of platelets in blood): 6 people, 20.00%
Hypoaesthesia (reduced sense of touch or sensation): 6 people, 20.00%
Weakness: 6 people, 20.00%
Joint Pain: 6 people, 20.00%
Nephrogenic Systemic Fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease): 5 people, 16.67%
Hyperkeratosis (thickening of the outer layer of the skin): 5 people, 16.67%

What are the existing conditions these people have? *

Pain: 5 people, 16.67%
Pemphigus (any of several acute or chronic skin diseases characterized by groups of itching blisters): 2 people, 6.67%
Nuclear Magnetic Resonance Imaging Brain: 2 people, 6.67%
High Blood Pressure: 2 people, 6.67%
Type 2 Diabetes: 1 person, 3.33%
Hallucinations (sensations that appear real but are created by your mind): 1 person, 3.33%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 3.33%
Delusion (a false belief or opinion): 1 person, 3.33%
Chest Pain: 1 person, 3.33%

* Approximation only. Some reports may have incomplete information.

Do you take Sinemet and have Purpura?

- Check whether Purpura is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sinemet:

Sinemet (29,601 reports)

Purpura treatments and more:

Purpura (10,762 reports)

Browse all side effects of Sinemet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Purpura:

Purpura (941 drugs)

Browse all the conditions that are associated with Purpura:

Purpura (1,515 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on carbidopa; levodopa (the active ingredients of Sinemet) and Sinemet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.