Singulair and Vena cava thrombosis - a phase IV clinical study of FDA data

Summary:

Vena cava thrombosis is reported as a side effect among people who take Singulair (montelukast sodium), especially for people who are female, 40-49 old, also take Yaz, and have Birth control.

The phase IV clinical study analyzes which people have Vena cava thrombosis when taking Singulair. It is created by eHealthMe based on reports of 125,532 people who have side effects when taking Singulair from the FDA, and is updated regularly.

What is Singulair?

Singulair has active ingredients of montelukast sodium. It is often used in asthma. eHealthMe is studying from 129,752 Singulair users. Check the latest studies of Singulair.

What is Vena cava thrombosis?

Vena cava thrombosis (clotting of the blood in large vein carrying deoxygenated blood into the heart) is found to be associated with 284 drugs and 464 conditions by eHealthMe. Check the latest studies of Vena cava thrombosis.

On Jul, 04, 2026

125,532 people reported to have side effects when taking Singulair.
Among them, 12 people (0.01%) have Vena cava thrombosis.

Could Singulair cause Vena cava thrombosis?

Among these 12 people:

What is the gender of people who have Vena cava thrombosis when taking Singulair? *

female: 91.67 %
male: 8.33 %

What is the age of people who have Vena cava thrombosis when taking Singulair? *

What are other drugs people take besides Singulair? *

What are other side effects people have besides Vena cava thrombosis? *

Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 6 people, 50.00%
Emotional Distress: 5 people, 41.67%
Injury: 5 people, 41.67%
Pain: 5 people, 41.67%
Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 33.33%
Stress And Anxiety: 4 people, 33.33%
Pelvic Venous Thrombosis (blood clot occurring inside a blood vessel and thromboses (dvts) that form in the deep veins of the legs or in the pelvic veins): 3 people, 25.00%
General Physical Health Deterioration (weak health status): 3 people, 25.00%
Subclavian Vein Thrombosis (abnormal condition in which a clot develops within the subclavian or axillary vein): 2 people, 16.67%
Thrombophlebitis Superficial (swelling (inflammation) of a superficial vein caused by a blood clot): 2 people, 16.67%

What are the existing conditions these people have? *

Birth Control: 3 people, 25.00%
Depression: 2 people, 16.67%
Cystic Fibrosis (disease of the secretary glands): 2 people, 16.67%
Respiratory Disorder (respiratory disease): 1 person, 8.33%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 8.33%
Polycystic Ovary Disease (cysts in the ovaries that occurs when the follicle stops developing): 1 person, 8.33%
Ovarian Cysts (fluid filled sacs of the ovary): 1 person, 8.33%
Nausea (feeling of having an urge to vomit): 1 person, 8.33%
Multiple Myeloma (cancer of the plasma cells): 1 person, 8.33%
High Blood Pressure: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Singulair and have Vena cava thrombosis?

- Check whether Vena cava thrombosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Singulair:

Singulair (129,752 reports)

Browse all side effects of Singulair:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Vena cava thrombosis:

Vena cava thrombosis (284 drugs)

Browse all the conditions that are associated with Vena cava thrombosis:

Vena cava thrombosis (464 conditions)

Related publications that referenced our studies

Das S, Mondal S, Dey JK, Bandyopadhyay S, Saha I, Tripathi SK, "A case of montelukast induced hypercholesterolemia, severe hypertriglyceridemia and pancreatitis", Journal of Young Pharmacists, 2013 Jun .
Das S, Mondal S, Dey JK, Bandyopadhyay S, Saha I, Tripathi SK, "A case of montelukast induced hypercholesterolemia, severe hypertriglyceridemia and pancreatitis", Journal of Young Pharmacists, 2013 Jun .

How the study uses the data?

The study uses data from the FDA. It is based on montelukast sodium (the active ingredients of Singulair) and Singulair (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.