Sirolimus and Aspergillosis - a phase IV clinical study of FDA data

Summary:

Aspergillosis is reported as a side effect among people who take Sirolimus (sirolimus), especially for people who are female, 50-59 old, also take Mycophenolate Mofetil, and have Immunodeficiency disorders.

The phase IV clinical study analyzes which people have Aspergillosis when taking Sirolimus. It is created by eHealthMe based on reports of 11,812 people who have side effects when taking Sirolimus from the FDA, and is updated regularly.

What is Sirolimus?

Sirolimus has active ingredients of sirolimus. eHealthMe is studying from 11,823 Sirolimus users. Check the latest studies of Sirolimus.

What is Aspergillosis?

Aspergillosis (an infection caused by a fungus called aspergillus) is found to be associated with 233 drugs and 531 conditions by eHealthMe. Check the latest studies of Aspergillosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

11,812 people reported to have side effects when taking Sirolimus.
Among them, 30 people (0.25%) have Aspergillosis.

Among these 30 people:

What is the gender of people who have Aspergillosis when taking Sirolimus? *

female: 51.85 %
male: 48.15 %

What is the age of people who have Aspergillosis when taking Sirolimus? *

What are other drugs people take besides Sirolimus? *

Mycophenolate Mofetil: 13 people, 43.33%
Methylprednisolone: 12 people, 40.00%
Cyclosporine: 8 people, 26.67%
Tacrolimus: 8 people, 26.67%
Fluconazole: 8 people, 26.67%
Azathioprine: 7 people, 23.33%
Prograf: 4 people, 13.33%
Prednisolone: 4 people, 13.33%
Voriconazole: 4 people, 13.33%
Prednisone: 3 people, 10.00%

What are other side effects people have besides Aspergillosis? *

Sepsis (a severe blood infection that can lead to organ failure and death): 8 people, 26.67%
Cytomegalovirus Infection: 7 people, 23.33%
Microangiopathy (disease of the capillaries (very small blood vessels), in which the capillary walls become so thick and weak that they bleed, leak protein): 5 people, 16.67%
Bacterial Sepsis: 4 people, 13.33%
Candida Sepsis (candida in blood stream): 4 people, 13.33%
Actinic Keratosis (skin disease due to sun exposure): 3 people, 10.00%
Kaposi's Sarcoma (a tumour caused by human herpes virus): 3 people, 10.00%
Pulmonary Cavitation (cavity in the lung): 3 people, 10.00%
Lung Neoplasm (tumour of lung): 3 people, 10.00%
Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 3 people, 10.00%

What are the existing conditions these people have? *

Immunodeficiency Disorders: 8 people, 26.67%
Transplant Rejection (a transplant material is not worked): 3 people, 10.00%
Renal Impairment (severely reduced kidney function): 2 people, 6.67%
Kaposi's Sarcoma (a tumour caused by human herpes virus): 2 people, 6.67%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 2 people, 6.67%
Bone Marrow Conditioning Regimen: 2 people, 6.67%
Stress And Anxiety: 1 person, 3.33%
Prostate Cancer: 1 person, 3.33%
Obliterative Bronchiolitis (bronchiolar inflammation): 1 person, 3.33%
Depression: 1 person, 3.33%

* Approximation only. Some reports may have incomplete information.

Do you take Sirolimus and have Aspergillosis?

- Check whether Aspergillosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sirolimus:

Sirolimus (11,823 reports)

Aspergillosis treatments and more:

Aspergillosis (4,156 reports)

Browse all side effects of Sirolimus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aspergillosis:

Aspergillosis (233 drugs)

Browse all the conditions that are associated with Aspergillosis:

Aspergillosis (531 conditions)

Related publications that referenced our studies

Biswal S, "Complete heart block in a neutropenic patient with aspergillosis: An unusual adverse effect of caspofungins", Journal of pharmacology & pharmacotherapeutics, 2012 Jan .
Biswal S, "Complete heart block in a neutropenic patient with aspergillosis: An unusual adverse effect of caspofungins", Journal of pharmacology & pharmacotherapeutics, 2012 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on sirolimus (the active ingredients of Sirolimus) and Sirolimus (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.