Sirolimus and Hepatitis b - a phase IV clinical study of FDA data

Summary:

Hepatitis b is reported as a side effect among people who take Sirolimus (sirolimus), especially for people who are male, 50-59 old, have been taking the drug for 2 - 5 years also take Cyclosporine, and have Immunodeficiency disorders.

The phase IV clinical study analyzes which people have Hepatitis b when taking Sirolimus. It is created by eHealthMe based on reports of 11,812 people who have side effects when taking Sirolimus from the FDA, and is updated regularly.

What is Sirolimus?

Sirolimus has active ingredients of sirolimus. eHealthMe is studying from 11,823 Sirolimus users. Check the latest studies of Sirolimus.

What is Hepatitis b?

Hepatitis b is found to be associated with 517 drugs and 683 conditions by eHealthMe. Check the latest studies of Hepatitis b.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

11,812 people reported to have side effects when taking Sirolimus.
Among them, 28 people (0.24%) have Hepatitis b.

Among these 28 people:

How long have people been on Sirolimus when they have Hepatitis b? *

What is the gender of people who have Hepatitis b when taking Sirolimus? *

female: 4.35 %
male: 95.65 %

What is the age of people who have Hepatitis b when taking Sirolimus? *

What are other drugs people take besides Sirolimus? *

What are other side effects people have besides Hepatitis b? *

Cytomegalovirus Infection: 10 people, 35.71%
Gastric Ulcer (stomach ulcer): 8 people, 28.57%
Tularaemia (an infection which can be spread from animals to humans to cause an acute, febrile, granulomatous infection): 8 people, 28.57%
Pneumonia Streptococcal (pneumonia, caused by streptococcus pneumoniae): 6 people, 21.43%
Acute Hepatic Failure: 5 people, 17.86%
Hypotension (abnormally low blood pressure): 4 people, 14.29%
Pneumonia Pneumococcal (pneumococcal pneumonia is a common but serious infection and inflammation of the lungs): 4 people, 14.29%
Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 4 people, 14.29%
Drug Ineffective: 3 people, 10.71%
Kidney Fibrosis (excess fibrous connective tissue in kidney): 3 people, 10.71%

What are the existing conditions these people have? *

Immunodeficiency Disorders: 9 people, 32.14%
Malignant Neoplasm Of Islets Of Langerhans (cancer tumour of pancreas): 6 people, 21.43%
Fever: 3 people, 10.71%
Uterine Leiomyosarcoma (uterus cancer of smooth muscle connective tissue): 2 people, 7.14%
Renal Impairment (severely reduced kidney function): 2 people, 7.14%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 2 people, 7.14%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 2 people, 7.14%
Multiple Myeloma (cancer of the plasma cells): 1 person, 3.57%
Metastases To Spleen (cancer spreads to spleen): 1 person, 3.57%
Metastases To Liver (cancer spreads to liver): 1 person, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Sirolimus and have Hepatitis b?

- Check whether Hepatitis b is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sirolimus:

Sirolimus (11,823 reports)

Hepatitis b treatments and more:

Hepatitis b (21,088 reports)

Browse all side effects of Sirolimus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatitis b:

Hepatitis b (517 drugs)

Browse all the conditions that are associated with Hepatitis b:

Hepatitis b (683 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sirolimus (the active ingredients of Sirolimus) and Sirolimus (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.