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Sitagliptin and Akathisia - a phase IV clinical study of FDA data

Summary:

Akathisia is reported as a side effect among people who take Sitagliptin (sitagliptin), especially for people who are male, 20-29 old, also take Amlodipine, and have Schizoaffective disorder.

The phase IV clinical study analyzes which people have Akathisia when taking Sitagliptin. It is created by eHealthMe based on reports of 3,929 people who have side effects when taking Sitagliptin from the FDA, and is updated regularly.

What is Sitagliptin?

Sitagliptin has active ingredients of sitagliptin. eHealthMe is studying from 3,933 Sitagliptin users. Check the latest studies of Sitagliptin.

What is Akathisia?

Akathisia (a movement disorder characterized by a feeling of inner restlessness) is found to be associated with 441 drugs and 822 conditions by eHealthMe. Check the latest studies of Akathisia.

On Jul, 09, 2026

3,929 people reported to have side effects when taking Sitagliptin.
Among them, 11 people (0.28%) have Akathisia.

Could Sitagliptin cause Akathisia?

Among these 11 people:

What is the gender of people who have Akathisia when taking Sitagliptin? *

  • female: 10 %
  • male: 90 %

What is the age of people who have Akathisia when taking Sitagliptin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 90 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 10 %

What are other drugs people take besides Sitagliptin? *

  1. Amlodipine: 9 people, 81.82%
  2. Perphenazine: 8 people, 72.73%
  3. Clonazepam: 8 people, 72.73%
  4. Levetiracetam: 8 people, 72.73%
  5. Diazepam: 8 people, 72.73%
  6. Olanzapine: 8 people, 72.73%
  7. Omeprazole: 8 people, 72.73%
  8. Paliperidone: 8 people, 72.73%
  9. Lactulose: 8 people, 72.73%
  10. Haloperidol: 8 people, 72.73%

What are other side effects people have besides Akathisia? *

  1. Drug Level Below Therapeutic: 9 people, 81.82%
  2. Overdose: 5 people, 45.45%
  3. Tremor (trembling or shaking movements in one or more parts of your body): 2 people, 18.18%
  4. Therapeutic Response Decreased (less preventive response): 2 people, 18.18%
  5. Fall: 2 people, 18.18%
  6. Broken Bone: 2 people, 18.18%
  7. Agitation (state of anxiety or nervous excitement): 2 people, 18.18%

What are the existing conditions these people have? *

  1. Tremor (trembling or shaking movements in one or more parts of your body): 9 people, 81.82%
  2. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 9 people, 81.82%
  3. Schizoaffective Disorder (a mental disorder characterized by disordered thought): 9 people, 81.82%
  4. High Blood Pressure: 8 people, 72.73%
  5. Psychotic Disorder: 7 people, 63.64%
  6. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 18.18%
  7. Bipolar Disorder (mood disorder): 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Sitagliptin and have Akathisia?

- Check whether Akathisia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sitagliptin:

Akathisia treatments and more:

How severe was Akathisia and when was it recovered:

Expand to all the drugs that have ingredients of sitagliptin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sitagliptin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Akathisia:

Browse all the conditions that are associated with Akathisia:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on sitagliptin (the active ingredients of Sitagliptin) and Sitagliptin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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