Sitagliptin and Rectal haemorrhage - a phase IV clinical study of FDA data

Summary:

Rectal haemorrhage is reported as a side effect among people who take Sitagliptin (sitagliptin), especially for people who are female, 60+ old, also take Metformin, and have Breast cancer metastatic.

The phase IV clinical study analyzes which people have Rectal haemorrhage when taking Sitagliptin. It is created by eHealthMe based on reports of 3,929 people who have side effects when taking Sitagliptin from the FDA, and is updated regularly.

What is Sitagliptin?

Sitagliptin has active ingredients of sitagliptin. eHealthMe is studying from 3,933 Sitagliptin users. Check the latest studies of Sitagliptin.

What is Rectal haemorrhage?

Rectal haemorrhage (bleeding from anus) is found to be associated with 1,729 drugs and 1,597 conditions by eHealthMe. Check the latest studies of Rectal haemorrhage.

On Jul, 08, 2026

3,929 people reported to have side effects when taking Sitagliptin.
Among them, 47 people (1.2%) have Rectal haemorrhage.

Could Sitagliptin cause Rectal haemorrhage?

Among these 47 people:

What is the gender of people who have Rectal haemorrhage when taking Sitagliptin? *

female: 82.5 %
male: 17.5 %

What is the age of people who have Rectal haemorrhage when taking Sitagliptin? *

What are other drugs people take besides Sitagliptin? *

Metformin: 41 people, 87.23%
Zoledronic Acid: 35 people, 74.47%
Amlodipine: 35 people, 74.47%
Gliclazide: 35 people, 74.47%
Linagliptin: 35 people, 74.47%
Zopiclone: 35 people, 74.47%
Rivaroxaban: 34 people, 72.34%
Magnesium Glycerophosphate: 32 people, 68.09%
Xgeva: 30 people, 63.83%
Taxotere: 28 people, 59.57%

What are other side effects people have besides Rectal haemorrhage? *

Diarrhea: 39 people, 82.98%
Weight Decreased: 35 people, 74.47%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 35 people, 74.47%
Urinary Tract Infection: 35 people, 74.47%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 35 people, 74.47%
Back Pain: 35 people, 74.47%
Rash Pruritic (redness with itching): 35 people, 74.47%
Gallstones (stone formation by bile component): 35 people, 74.47%
Nausea And Vomiting: 35 people, 74.47%
Pulmonary Embolism (blockage of the main artery of the lung): 31 people, 65.96%

What are the existing conditions these people have? *

Glossodynia (a burning or painful sensation in the tongue): 35 people, 74.47%
Gastrointestinal Motility Disorder (abnormal intestinal contractions): 35 people, 74.47%
Blood Potassium Decreased: 35 people, 74.47%
Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 35 people, 74.47%
High Blood Pressure: 35 people, 74.47%
Breast Cancer Metastatic: 35 people, 74.47%
Blood Phosphorus Decreased: 34 people, 72.34%
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood): 34 people, 72.34%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 32 people, 68.09%
Urinary Tract Infection: 31 people, 65.96%

* Approximation only. Some reports may have incomplete information.

Do you take Sitagliptin and have Rectal haemorrhage?

- Check whether Rectal haemorrhage is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sitagliptin:

Sitagliptin (3,933 reports)

Browse all side effects of Sitagliptin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rectal haemorrhage:

Rectal haemorrhage (1,729 drugs)

Browse all the conditions that are associated with Rectal haemorrhage:

Rectal haemorrhage (1,597 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sitagliptin (the active ingredients of Sitagliptin) and Sitagliptin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.