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Skytrofa and Fatigue aggravated - a phase IV clinical study of FDA data

Summary:

Fatigue aggravated is reported as a side effect among people who take Skytrofa (lonapegsomatropin-tcgd), especially for people who are male, 2-9 old, have been taking the drug for < 1 month also take Cyproheptadine Hydrochloride, and have Growth hormone deficiency.

The phase IV clinical study analyzes which people have Fatigue aggravated when taking Skytrofa. It is created by eHealthMe based on reports of 495 people who have side effects when taking Skytrofa from the FDA, and is updated regularly.

What is Skytrofa?

Skytrofa has active ingredients of lonapegsomatropin-tcgd. eHealthMe is studying from 495 Skytrofa users. Check the latest studies of Skytrofa.

What is Fatigue aggravated?

Fatigue aggravated (feeling of tiredness) is found to be associated with 3,119 drugs and 1,116 conditions by eHealthMe. Check the latest studies of Fatigue aggravated.

On Jul, 20, 2026

495 people reported to have side effects when taking Skytrofa.
Among them, 17 people (3.43%) have Fatigue aggravated.

Could Skytrofa cause Fatigue aggravated?

Among these 17 people:

How long have people been on Skytrofa when they have Fatigue aggravated? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Fatigue aggravated when taking Skytrofa? *

  • female: 0.0 %
  • male: 100 %

What is the age of people who have Fatigue aggravated when taking Skytrofa? *

  • 0-1: 0.0 %
  • 2-9: 100 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

What are other drugs people take besides Skytrofa? *

  1. Cyproheptadine Hydrochloride: 2 people, 11.76%
  2. Vitamins: 1 person, 5.88%
  3. Furosemide: 1 person, 5.88%
  4. Anastrozole: 1 person, 5.88%
  5. Aspirin: 1 person, 5.88%
  6. Bisacodyl: 1 person, 5.88%
  7. Flovent: 1 person, 5.88%
  8. Focalin: 1 person, 5.88%
  9. Hydrocortisone: 1 person, 5.88%
  10. Solu-Cortef: 1 person, 5.88%

What are other side effects people have besides Fatigue aggravated? *

  1. Nausea And Vomiting: 6 people, 35.29%
  2. Nasopharyngitis (inflammation of the nasopharynx): 4 people, 23.53%
  3. Dizziness: 4 people, 23.53%
  4. Rhinorrhea (watery mucus discharge from the nose): 3 people, 17.65%
  5. Abdominal Pain Upper: 3 people, 17.65%
  6. Sneezing: 3 people, 17.65%
  7. Nausea (feeling of having an urge to vomit): 3 people, 17.65%
  8. Joint Pain: 3 people, 17.65%
  9. Drowsiness: 3 people, 17.65%
  10. Abdominal Pain: 3 people, 17.65%

What are the existing conditions these people have? *

  1. Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 9 people, 52.94%
  2. Growth Hormone Deficiency: 9 people, 52.94%

* Approximation only. Some reports may have incomplete information.

Do you take Skytrofa and have Fatigue aggravated?

- Check whether Fatigue aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Skytrofa:

Fatigue aggravated treatments and more:

How severe was Fatigue aggravated and when was it recovered:

Expand to all the drugs that have ingredients of lonapegsomatropin-tcgd:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Skytrofa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fatigue aggravated:

Browse all the conditions that are associated with Fatigue aggravated:

How the study uses the data?

The study uses data from the FDA. It is based on lonapegsomatropin-tcgd (the active ingredients of Skytrofa) and Skytrofa (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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