Sodium bicarbonate and Hyperreflexia - a phase IV clinical study of FDA data

Summary:

Hyperreflexia is reported as a side effect among people who take Sodium bicarbonate (sodium bicarbonate), especially for people who are female, 30-39 old, also take Dimenhydrinate, and have Morning sickness.

The phase IV clinical study analyzes which people have Hyperreflexia when taking Sodium bicarbonate. It is created by eHealthMe based on reports of 27,114 people who have side effects when taking Sodium bicarbonate from the FDA, and is updated regularly.

What is Sodium bicarbonate?

Sodium bicarbonate has active ingredients of sodium bicarbonate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 27,283 Sodium bicarbonate users. Check the latest studies of Sodium bicarbonate.

What is Hyperreflexia?

Hyperreflexia (overactive or over responsive reflexes) is found to be associated with 418 drugs and 651 conditions by eHealthMe. Check the latest studies of Hyperreflexia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

27,114 people reported to have side effects when taking Sodium bicarbonate.
Among them, 25 people (0.09%) have Hyperreflexia.

Could Sodium bicarbonate cause Hyperreflexia?

Among these 25 people:

What is the gender of people who have Hyperreflexia when taking Sodium bicarbonate? *

female: 77.27 %
male: 22.73 %

What is the age of people who have Hyperreflexia when taking Sodium bicarbonate? *

What are other drugs people take besides Sodium bicarbonate? *

Ondansetron: 17 people, 68.00%
Prochlorperazine: 17 people, 68.00%
Famotidine: 17 people, 68.00%
Lorazepam: 17 people, 68.00%
Dimenhydrinate: 17 people, 68.00%
Acetaminophen: 15 people, 60.00%
Pyridoxine: 15 people, 60.00%
Sumatriptan: 14 people, 56.00%
Sumatriptan Succinate: 12 people, 48.00%
Doxylamine Succinate: 11 people, 44.00%

What are other side effects people have besides Hyperreflexia? *

Clonus (series of involuntary, rhythmic, muscular contractions and relaxations): 23 people, 92.00%
Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 20 people, 80.00%
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch): 19 people, 76.00%
Tremor (trembling or shaking movements in one or more parts of your body): 18 people, 72.00%
Fever: 18 people, 72.00%
Drug Ineffective: 18 people, 72.00%
Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 18 people, 72.00%
Arrhythmias (irregular heartbeat): 18 people, 72.00%
Abortion Spontaneous (naturally occurring miscarriage): 17 people, 68.00%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 17 people, 68.00%

What are the existing conditions these people have? *

Migraine (headache): 17 people, 68.00%
Morning Sickness (sickness in morning during pregnancy): 17 people, 68.00%
Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 16 people, 64.00%
Nausea (feeling of having an urge to vomit): 16 people, 64.00%
Hyperemesis Gravidarum (a condition characterized by severe nausea, vomiting, weight loss, and electrolyte disturbance): 16 people, 64.00%
Body Temperature Increased: 14 people, 56.00%
Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 12 people, 48.00%
Fever: 11 people, 44.00%
Depression: 4 people, 16.00%
Stress And Anxiety: 3 people, 12.00%

* Approximation only. Some reports may have incomplete information.

Do you take Sodium bicarbonate and have Hyperreflexia?

- Check whether Hyperreflexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sodium bicarbonate:

Sodium bicarbonate (27,283 reports)

Hyperreflexia treatments and more:

Hyperreflexia (4,677 reports)

Browse all side effects of Sodium bicarbonate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperreflexia:

Hyperreflexia (418 drugs)

Browse all the conditions that are associated with Hyperreflexia:

Hyperreflexia (651 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sodium bicarbonate (the active ingredients of Sodium bicarbonate) and Sodium bicarbonate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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