Sofosbuvir and Hypoaesthesia - a phase IV clinical study of FDA data

Summary:

Hypoaesthesia is reported as a side effect among people who take Sofosbuvir (sofosbuvir), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Pegasys, and have Hepatitis c.

The phase IV clinical study analyzes which people have Hypoaesthesia when taking Sofosbuvir. It is created by eHealthMe based on reports of 9,193 people who have side effects when taking Sofosbuvir from the FDA, and is updated regularly.

What is Sofosbuvir?

Sofosbuvir has active ingredients of sofosbuvir. eHealthMe is studying from 9,194 Sofosbuvir users. Check the latest studies of Sofosbuvir.

What is Hypoaesthesia?

Hypoaesthesia (reduced sense of touch or sensation) is found to be associated with 2,888 drugs and 3,185 conditions by eHealthMe. Check the latest studies of Hypoaesthesia.



On Aug, 02, 2026

9,193 people reported to have side effects when taking Sofosbuvir.
Among them, 24 people (0.26%) have Hypoaesthesia.

Could Sofosbuvir cause Hypoaesthesia?

Among these 24 people:

How long have people been on Sofosbuvir when they have Hypoaesthesia? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypoaesthesia when taking Sofosbuvir? *

  • female: 52.17 %
  • male: 47.83 %

What is the age of people who have Hypoaesthesia when taking Sofosbuvir? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 13.04 %
  • 40-49: 13.04 %
  • 50-59: 52.17 %
  • 60+: 21.74 %

What are other drugs people take besides Sofosbuvir? *

  1. Pegasys: 4 people, 16.67%
  2. Dexilant: 3 people, 12.50%
  3. Neurontin: 3 people, 12.50%
  4. Daklinza: 2 people, 8.33%
  5. Pegintron: 2 people, 8.33%
  6. Olysio: 2 people, 8.33%
  7. Zoloft: 1 person, 4.17%
  8. Keppra: 1 person, 4.17%
  9. Bendamustine: 1 person, 4.17%
  10. Bortezomib: 1 person, 4.17%

What are other side effects people have besides Hypoaesthesia? *

  1. Fatigue (feeling of tiredness): 9 people, 37.50%
  2. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 8 people, 33.33%
  3. Weakness: 6 people, 25.00%
  4. Headache (pain in head): 6 people, 25.00%
  5. Dyspnea (difficult or laboured breathing): 6 people, 25.00%
  6. Joint Pain: 6 people, 25.00%
  7. Malaise (a feeling of general discomfort or uneasiness): 6 people, 25.00%
  8. Memory Loss: 5 people, 20.83%
  9. Neuropathy Peripheral (surface nerve damage): 5 people, 20.83%
  10. Nausea (feeling of having an urge to vomit): 5 people, 20.83%

What are the existing conditions these people have? *

  1. Hepatitis C: 10 people, 41.67%
  2. Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 2 people, 8.33%
  3. Stress And Anxiety: 2 people, 8.33%
  4. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 4.17%
  5. Pulmonary Tuberculosis (lungs tuberculosis): 1 person, 4.17%
  6. Neuropathy Peripheral (surface nerve damage): 1 person, 4.17%
  7. Neoplasm Malignant (cancer tumour): 1 person, 4.17%
  8. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 1 person, 4.17%
  9. Liver Disorder (liver diseases): 1 person, 4.17%
  10. Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Sofosbuvir and have Hypoaesthesia?

- Check whether Hypoaesthesia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sofosbuvir:

Hypoaesthesia treatments and more:

How severe was Hypoaesthesia and when was it recovered:

Expand to all the drugs that have ingredients of sofosbuvir:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sofosbuvir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypoaesthesia:

Browse all the conditions that are associated with Hypoaesthesia:


How the study uses the data?

The study uses data from the FDA. It is based on sofosbuvir (the active ingredients of Sofosbuvir) and Sofosbuvir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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