Soliris and Blood uric acid increased - a phase IV clinical study of FDA data

Summary:

Blood uric acid increased is reported as a side effect among people who take Soliris (eculizumab), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Aranesp, and have Paroxysmal nocturnal haemoglobinuria.

The phase IV clinical study analyzes which people have Blood uric acid increased when taking Soliris. It is created by eHealthMe based on reports of 58,774 people who have side effects when taking Soliris from the FDA, and is updated regularly.

What is Soliris?

Soliris has active ingredients of eculizumab. It is often used in paroxysmal nocturnal hemoglobinuria (pnh). eHealthMe is studying from 58,821 Soliris users. Check the latest studies of Soliris.

What is Blood uric acid increased?

Blood uric acid increased is found to be associated with 756 drugs and 959 conditions by eHealthMe. Check the latest studies of Blood uric acid increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

58,774 people reported to have side effects when taking Soliris.
Among them, 13 people (0.02%) have Blood uric acid increased.

Could Soliris cause Blood uric acid increased?

Among these 13 people:

How long have people been on Soliris when they have Blood uric acid increased? *

What is the gender of people who have Blood uric acid increased when taking Soliris? *

female: 77.78 %
male: 22.22 %

What is the age of people who have Blood uric acid increased when taking Soliris? *

What are other drugs people take besides Soliris? *

What are other side effects people have besides Blood uric acid increased? *

Blood Urea Increased: 6 people, 46.15%
Haemoglobin Decreased: 4 people, 30.77%
Red Blood Cell Count Decreased: 4 people, 30.77%
Renal Impairment (severely reduced kidney function): 3 people, 23.08%
Haematocrit Decreased: 3 people, 23.08%
Blood Alkaline Phosphatase Increased: 3 people, 23.08%
Neutrophil Count Increased (excess than normal number of neutrophil a type of blood cell): 2 people, 15.38%
Glomerular Filtration Rate Decreased: 2 people, 15.38%
Blood Creatinine Increased: 2 people, 15.38%
Blood Bilirubin Increased: 2 people, 15.38%

What are the existing conditions these people have? *

Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 5 people, 38.46%
Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 3 people, 23.08%
Stress And Anxiety: 1 person, 7.69%
Pinworms: 1 person, 7.69%
Insomnia (sleeplessness): 1 person, 7.69%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 1 person, 7.69%
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 1 person, 7.69%
Hyperkalemia (damage to or disease of the kidney): 1 person, 7.69%
High Blood Pressure: 1 person, 7.69%
Hepatitis C: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Soliris and have Blood uric acid increased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Soliris:

Soliris (58,821 reports)

Browse all side effects of Soliris:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Blood uric acid increased:

Blood uric acid increased (756 drugs)

Browse all the conditions that are associated with Blood uric acid increased:

Blood uric acid increased (959 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on eculizumab (the active ingredients of Soliris) and Soliris (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.