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Soliris and Fibrin d dimer increased - a phase IV clinical study of FDA data

Summary:

Fibrin d dimer increased is reported as a side effect among people who take Soliris (eculizumab), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Neoral, and have Paroxysmal nocturnal haemoglobinuria.

The phase IV clinical study analyzes which people have Fibrin d dimer increased when taking Soliris. It is created by eHealthMe based on reports of 58,774 people who have side effects when taking Soliris from the FDA, and is updated regularly.

What is Soliris?

Soliris has active ingredients of eculizumab. It is often used in paroxysmal nocturnal hemoglobinuria (pnh). eHealthMe is studying from 58,821 Soliris users. Check the latest studies of Soliris.

What is Fibrin d dimer increased?

Fibrin d dimer increased is found to be associated with 517 drugs and 834 conditions by eHealthMe. Check the latest studies of Fibrin d dimer increased.

On Jul, 14, 2026

58,774 people reported to have side effects when taking Soliris.
Among them, 54 people (0.09%) have Fibrin d dimer increased.

Could Soliris cause Fibrin d dimer increased?

Among these 54 people:

How long have people been on Soliris when they have Fibrin d dimer increased? *

  • < 1 month: 57.14 %
  • 1 - 6 months: 14.29 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 14.29 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 14.29 %
  • 10+ years: 0.0 %

What is the gender of people who have Fibrin d dimer increased when taking Soliris? *

  • female: 69.57 %
  • male: 30.43 %

What is the age of people who have Fibrin d dimer increased when taking Soliris? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 9.68 %
  • 20-29: 12.9 %
  • 30-39: 19.35 %
  • 40-49: 6.45 %
  • 50-59: 19.35 %
  • 60+: 32.26 %

What are other drugs people take besides Soliris? *

  1. Requip: 2 people, 3.70%
  2. Protonix: 2 people, 3.70%
  3. Clexane: 2 people, 3.70%
  4. Cyclosporine: 2 people, 3.70%
  5. Neoral: 2 people, 3.70%
  6. Zofran: 1 person, 1.85%
  7. Lovenox: 1 person, 1.85%
  8. Azathioprine: 1 person, 1.85%
  9. Calcium: 1 person, 1.85%
  10. Erlotinib Hydrochloride: 1 person, 1.85%

What are other side effects people have besides Fibrin d dimer increased? *

  1. Haemoglobin Decreased: 24 people, 44.44%
  2. Thrombocytopenia (decrease of platelets in blood): 16 people, 29.63%
  3. Blood Lactate Dehydrogenase Increased: 10 people, 18.52%
  4. Haematocrit Decreased: 10 people, 18.52%
  5. Fatigue (feeling of tiredness): 9 people, 16.67%
  6. Disseminated Intravascular Coagulation (systemic activation of blood coagulation): 8 people, 14.81%
  7. Fever: 8 people, 14.81%
  8. Reticulocyte Count Increased: 8 people, 14.81%
  9. White Blood Cell Count Decreased: 8 people, 14.81%
  10. Red Blood Cell Count Decreased: 7 people, 12.96%

What are the existing conditions these people have? *

  1. Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 35 people, 64.81%
  2. Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 4 people, 7.41%
  3. Microangiopathic Haemolytic Anaemia (anaemia due to inability of bone marrow to compensate the premature destruction of red blood cells): 3 people, 5.56%
  4. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 3 people, 5.56%
  5. Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 3 people, 5.56%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 3.70%
  7. Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 3.70%
  8. Nausea (feeling of having an urge to vomit): 2 people, 3.70%
  9. Thrombotic Microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury): 2 people, 3.70%
  10. Aplasia (defective development or congenital absence of an organ or tissue): 1 person, 1.85%

* Approximation only. Some reports may have incomplete information.

Do you take Soliris and have Fibrin d dimer increased?

- Check whether Fibrin d dimer increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Soliris:

Fibrin d dimer increased treatments and more:

How severe was Fibrin d dimer increased and when was it recovered:

Expand to all the drugs that have ingredients of eculizumab:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Soliris:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fibrin d dimer increased:

Browse all the conditions that are associated with Fibrin d dimer increased:

How the study uses the data?

The study uses data from the FDA. It is based on eculizumab (the active ingredients of Soliris) and Soliris (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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