Soliris and Myopathy - a phase IV clinical study of FDA data

Summary:

Myopathy is reported as a side effect among people who take Soliris (eculizumab), especially for people who are male, 30-39 old, have been taking the drug for 6 - 12 months also take Ibrutinib, and have Thrombotic microangiopathy.

The phase IV clinical study analyzes which people have Myopathy when taking Soliris. It is created by eHealthMe based on reports of 58,774 people who have side effects when taking Soliris from the FDA, and is updated regularly.

What is Soliris?

Soliris has active ingredients of eculizumab. It is often used in paroxysmal nocturnal hemoglobinuria (pnh). eHealthMe is studying from 58,821 Soliris users. Check the latest studies of Soliris.

What is Myopathy?

Myopathy (a muscular disease in which the muscle fibres do not function) is found to be associated with 825 drugs and 1,015 conditions by eHealthMe. Check the latest studies of Myopathy.

On Apr, 01, 2026

58,774 people reported to have side effects when taking Soliris.
Among them, 18 people (0.03%) have Myopathy.

Among these 18 people:

How long have people been on Soliris when they have Myopathy? *

What is the gender of people who have Myopathy when taking Soliris? *

female: 16.67 %
male: 83.33 %

What is the age of people who have Myopathy when taking Soliris? *

What are other drugs people take besides Soliris? *

What are other side effects people have besides Myopathy? *

Reticulocyte Count Increased: 15 people, 83.33%
Thrombotic Microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury): 14 people, 77.78%
Haemolytic Anaemia (anaemia due to haemolysis): 12 people, 66.67%
Acute Kidney Failure: 11 people, 61.11%
Thrombocytopenia (decrease of platelets in blood): 11 people, 61.11%
Cytomegalovirus Infection: 10 people, 55.56%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 10 people, 55.56%
Human Herpesvirus 6 Infection: 9 people, 50.00%
Chronic Graft Versus Host Disease (immune cells attack the host's body cells after transplant): 5 people, 27.78%
Pain In Extremity: 2 people, 11.11%

What are the existing conditions these people have? *

Thrombotic Microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury): 15 people, 83.33%
Graft Versus Host Disease In Skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin): 14 people, 77.78%
Bone Marrow Conditioning Regimen: 11 people, 61.11%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 8 people, 44.44%
Lymphoma (cancer that begins in immune system cells): 4 people, 22.22%
Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 2 people, 11.11%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1 person, 5.56%
Disease Recurrence: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Soliris and have Myopathy?

- Check whether Myopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Soliris:

Soliris (58,821 reports)

Myopathy treatments and more:

Myopathy (12,767 reports)

Browse all side effects of Soliris:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Myopathy:

Myopathy (825 drugs)

Browse all the conditions that are associated with Myopathy:

Myopathy (1,015 conditions)

Related publications that referenced our studies

Das S, Anand Ramasamy SD, Mondal S, "An unusual case of glipizide-induced proximal myopathy", Journal of pharmacology & pharmacotherapeutics, 2016 Jan .
Das S, Anand Ramasamy SD, Mondal S, "An unusual case of glipizide-induced proximal myopathy", Journal of pharmacology & pharmacotherapeutics, 2016 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on eculizumab (the active ingredients of Soliris) and Soliris (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.