Soliris and Parkinsonism aggravated - a phase IV clinical study of FDA data

Summary:

Parkinsonism aggravated is reported as a side effect among people who take Soliris (eculizumab), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Cyclosporine, and have Paroxysmal nocturnal haemoglobinuria.

The phase IV clinical study analyzes which people have Parkinsonism aggravated when taking Soliris. It is created by eHealthMe based on reports of 58,774 people who have side effects when taking Soliris from the FDA, and is updated regularly.

What is Soliris?

Soliris has active ingredients of eculizumab. It is often used in paroxysmal nocturnal hemoglobinuria (pnh). eHealthMe is studying from 58,821 Soliris users. Check the latest studies of Soliris.

What is Parkinsonism aggravated?

Parkinsonism aggravated (a degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination) is found to be associated with 1,025 drugs and 343 conditions by eHealthMe. Check the latest studies of Parkinsonism aggravated.

On Aug, 09, 2026

58,774 people reported to have side effects when taking Soliris.
Among them, 13 people (0.02%) have Parkinsonism aggravated.

Could Soliris cause Parkinsonism aggravated?

Among these 13 people:

How long have people been on Soliris when they have Parkinsonism aggravated? *

What is the gender of people who have Parkinsonism aggravated when taking Soliris? *

female: 88.89 %
male: 11.11 %

What is the age of people who have Parkinsonism aggravated when taking Soliris? *

What are other drugs people take besides Soliris? *

What are other side effects people have besides Parkinsonism aggravated? *

Tremor (trembling or shaking movements in one or more parts of your body): 6 people, 46.15%
Intracranial Pressure Increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid): 3 people, 23.08%
Parkinsonian Gait (gait exhibited by patients suffering from parkinson's disease): 3 people, 23.08%
Carpal Tunnel Syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 3 people, 23.08%
Sleep Disorder: 3 people, 23.08%
Dyspnea Exertional: 3 people, 23.08%
Depression: 3 people, 23.08%
Haemoglobin Decreased: 3 people, 23.08%
Fall: 2 people, 15.38%
Fatigue (feeling of tiredness): 2 people, 15.38%

What are the existing conditions these people have? *

Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 8 people, 61.54%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 7.69%
Joint Pain: 1 person, 7.69%
Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 1 person, 7.69%
Back Pain: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Soliris and have Parkinsonism aggravated?

- Check whether Parkinsonism aggravated is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Soliris:

Soliris (58,821 reports)

Browse all side effects of Soliris:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Parkinsonism aggravated:

Parkinsonism aggravated (1,026 drugs)

Browse all the conditions that are associated with Parkinsonism aggravated:

Parkinsonism aggravated (343 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on eculizumab (the active ingredients of Soliris) and Soliris (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.