Solu-cortef and Hypotonia - a phase IV clinical study of FDA data

Summary:

Hypotonia is reported as a side effect among people who take Solu-cortef (hydrocortisone sodium succinate), especially for people who are female, 0-1 old, have been taking the drug for 1 - 6 months also take Synthroid, and have Constipation.

The phase IV clinical study analyzes which people have Hypotonia when taking Solu-cortef. It is created by eHealthMe based on reports of 7,966 people who have side effects when taking Solu-cortef from the FDA, and is updated regularly.

What is Solu-cortef?

Solu-cortef has active ingredients of hydrocortisone sodium succinate. eHealthMe is studying from 7,983 Solu-cortef users. Check the latest studies of Solu-cortef.

What is Hypotonia?

Hypotonia (low muscle tone) is found to be associated with 824 drugs and 1,770 conditions by eHealthMe. Check the latest studies of Hypotonia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

7,966 people reported to have side effects when taking Solu-cortef.
Among them, 16 people (0.2%) have Hypotonia.

Among these 16 people:

How long have people been on Solu-cortef when they have Hypotonia? *

What is the gender of people who have Hypotonia when taking Solu-cortef? *

female: 62.5 %
male: 37.5 %

What is the age of people who have Hypotonia when taking Solu-cortef? *

What are other drugs people take besides Solu-cortef? *

What are other side effects people have besides Hypotonia? *

Weight Decreased: 8 people, 50.00%
Confusional State: 6 people, 37.50%
Abdominal Pain: 6 people, 37.50%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 5 people, 31.25%
Poor Quality Sleep: 5 people, 31.25%
Haematochezia (passage of stools containing blood): 5 people, 31.25%
Growth Retardation (delayed growth): 5 people, 31.25%
Fever: 5 people, 31.25%
Hyperacusis (disorder in loudness perception): 5 people, 31.25%
Hypernatraemia (an abnormally high plasma concentration of sodium ions): 5 people, 31.25%

What are the existing conditions these people have? *

Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 5 people, 31.25%
Growth Hormone Deficiency: 5 people, 31.25%
Constipation: 5 people, 31.25%
Iron Deficiency Anaemia: 4 people, 25.00%
Depression: 4 people, 25.00%
Fungal Infection: 2 people, 12.50%
Pain: 1 person, 6.25%
Neuromuscular Blockade Reversal: 1 person, 6.25%
Infantile Spasms: 1 person, 6.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Solu-cortef and have Hypotonia?

- Check whether Hypotonia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Solu-cortef:

Solu-cortef (7,983 reports)

Hypotonia treatments and more:

Hypotonia (14,614 reports)

How severe was Hypotonia and when was it recovered:

Hypotonia in Solu-cortef

Expand to all the drugs that have ingredients of hydrocortisone sodium succinate:

Hypotonia and drugs with ingredients of hydrocortisone sodium succinate (19 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Solu-cortef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypotonia:

Hypotonia (824 drugs)

Browse all the conditions that are associated with Hypotonia:

Hypotonia (1,770 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone sodium succinate (the active ingredients of Solu-cortef) and Solu-cortef (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.