Solu-cortef and Synovitis - a phase IV clinical study of FDA data

Summary:

Synovitis is reported as a side effect among people who take Solu-cortef (hydrocortisone sodium succinate), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Prednisolone, and have Arthritis.

The phase IV clinical study analyzes which people have Synovitis when taking Solu-cortef. It is created by eHealthMe based on reports of 7,966 people who have side effects when taking Solu-cortef from the FDA, and is updated regularly.

What is Solu-cortef?

Solu-cortef has active ingredients of hydrocortisone sodium succinate. eHealthMe is studying from 7,983 Solu-cortef users. Check the latest studies of Solu-cortef.

What is Synovitis?

Synovitis (inflammation of the synovial membrane) is found to be associated with 695 drugs and 509 conditions by eHealthMe. Check the latest studies of Synovitis.

On Jul, 11, 2026

7,966 people reported to have side effects when taking Solu-cortef.
Among them, 15 people (0.19%) have Synovitis.

Among these 15 people:

How long have people been on Solu-cortef when they have Synovitis? *

What is the gender of people who have Synovitis when taking Solu-cortef? *

female: 75 %
male: 25 %

What is the age of people who have Synovitis when taking Solu-cortef? *

What are other drugs people take besides Solu-cortef? *

What are other side effects people have besides Synovitis? *

Joint Pain: 12 people, 80.00%
Joint Swelling: 12 people, 80.00%
Joint Stiffness: 10 people, 66.67%
Itching: 9 people, 60.00%
Drug Ineffective: 9 people, 60.00%
Skin Disorder (skin disease): 8 people, 53.33%
Infection: 8 people, 53.33%
Hypersensitivity: 8 people, 53.33%
Feeling Cold: 8 people, 53.33%
Infusion Related Reaction: 8 people, 53.33%

What are the existing conditions these people have? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 8 people, 53.33%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 8 people, 53.33%
Muscle Aches (muscle pain): 6 people, 40.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 26.67%
Nausea (feeling of having an urge to vomit): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Solu-cortef and have Synovitis?

- Check whether Synovitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Solu-cortef:

Solu-cortef (7,983 reports)

Synovitis treatments and more:

Synovitis (24,130 reports)

How severe was Synovitis and when was it recovered:

Synovitis in Solu-cortef

Expand to all the drugs that have ingredients of hydrocortisone sodium succinate:

Synovitis and drugs with ingredients of hydrocortisone sodium succinate (271 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Solu-cortef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Synovitis:

Synovitis (695 drugs)

Browse all the conditions that are associated with Synovitis:

Synovitis (509 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone sodium succinate (the active ingredients of Solu-cortef) and Solu-cortef (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.