Solu-medrol and Diastolic dysfunction - a phase IV clinical study of FDA data

Summary:

Diastolic dysfunction is reported as a side effect among people who take Solu-medrol (methylprednisolone sodium succinate), especially for people who are male, 60+ old, also take Ativan, and have Myositis.

The phase IV clinical study analyzes which people have Diastolic dysfunction when taking Solu-medrol. It is created by eHealthMe based on reports of 39,265 people who have side effects when taking Solu-medrol from the FDA, and is updated regularly.

What is Solu-medrol?

Solu-medrol has active ingredients of methylprednisolone sodium succinate. It is often used in multiple sclerosis. eHealthMe is studying from 39,410 Solu-medrol users. Check the latest studies of Solu-medrol.

What is Diastolic dysfunction?

Diastolic dysfunction is found to be associated with 677 drugs and 631 conditions by eHealthMe. Check the latest studies of Diastolic dysfunction.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

39,265 people reported to have side effects when taking Solu-medrol.
Among them, 33 people (0.08%) have Diastolic dysfunction.

Could Solu-medrol cause Diastolic dysfunction?

Among these 33 people:

What is the gender of people who have Diastolic dysfunction when taking Solu-medrol? *

female: 39.29 %
male: 60.71 %

What is the age of people who have Diastolic dysfunction when taking Solu-medrol? *

What are other drugs people take besides Solu-medrol? *

What are other side effects people have besides Diastolic dysfunction? *

Drug Ineffective: 15 people, 45.45%
Heart Rate Decreased: 15 people, 45.45%
Oxygen Saturation Decreased: 13 people, 39.39%
Body Temperature Decreased: 12 people, 36.36%
Cytomegalovirus Infection: 12 people, 36.36%
Infusion Related Reaction: 12 people, 36.36%
Weight Decreased: 12 people, 36.36%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 11 people, 33.33%
Blood Pressure Fluctuation: 9 people, 27.27%
Acute Kidney Failure: 8 people, 24.24%

What are the existing conditions these people have? *

Myositis (inflammation of the muscles): 12 people, 36.36%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 12.12%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 2 people, 6.06%
Injury: 1 person, 3.03%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 3.03%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 3.03%
Colon Cancer: 1 person, 3.03%
Constipation: 1 person, 3.03%
Dyspnea (difficult or laboured breathing): 1 person, 3.03%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1 person, 3.03%

* Approximation only. Some reports may have incomplete information.

Do you take Solu-medrol and have Diastolic dysfunction?

- Check whether Diastolic dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Solu-medrol:

Solu-medrol (39,410 reports)

Diastolic dysfunction treatments and more:

Diastolic dysfunction (4,665 reports)

How severe was Diastolic dysfunction and when was it recovered:

Diastolic dysfunction in Solu-medrol

Expand to all the drugs that have ingredients of methylprednisolone sodium succinate:

Diastolic dysfunction and drugs with ingredients of methylprednisolone sodium succinate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Solu-medrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diastolic dysfunction:

Diastolic dysfunction (677 drugs)

Browse all the conditions that are associated with Diastolic dysfunction:

Diastolic dysfunction (631 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methylprednisolone sodium succinate (the active ingredients of Solu-medrol) and Solu-medrol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.