Solu-medrol and Lower extremity mass - a phase IV clinical study of FDA data

Summary:

Lower extremity mass is reported as a side effect among people who take Solu-medrol (methylprednisolone sodium succinate), especially for people who are male, 50-59 old, also take Baclofen, and have Gastric ulcer.

The phase IV clinical study analyzes which people have Lower extremity mass when taking Solu-medrol. It is created by eHealthMe based on reports of 39,265 people who have side effects when taking Solu-medrol from the FDA, and is updated regularly.

What is Solu-medrol?

Solu-medrol has active ingredients of methylprednisolone sodium succinate. It is often used in multiple sclerosis. eHealthMe is studying from 39,410 Solu-medrol users. Check the latest studies of Solu-medrol.

What is Lower extremity mass?

Lower extremity mass (mass in lower legs) is found to be associated with 168 drugs and 298 conditions by eHealthMe. Check the latest studies of Lower extremity mass.

On Jul, 05, 2026

39,265 people reported to have side effects when taking Solu-medrol.
Among them, 13 people (0.03%) have Lower extremity mass.

Could Solu-medrol cause Lower extremity mass?

Among these 13 people:

What is the gender of people who have Lower extremity mass when taking Solu-medrol? *

female: 8.33 %
male: 91.67 %

What is the age of people who have Lower extremity mass when taking Solu-medrol? *

What are other drugs people take besides Solu-medrol? *

What are other side effects people have besides Lower extremity mass? *

Rashes (redness): 13 people, 100.00%
Transaminases Increased: 12 people, 92.31%
Impaired Healing: 12 people, 92.31%
Haemoglobin Decreased: 12 people, 92.31%
Headache (pain in head): 12 people, 92.31%
High Blood Pressure: 12 people, 92.31%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 12 people, 92.31%
Hypokalemia (low potassium): 12 people, 92.31%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 12 people, 92.31%
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood): 12 people, 92.31%

What are the existing conditions these people have? *

Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 7.69%
Staphylococcal Infection (an infection with staphylococcus bacteria): 1 person, 7.69%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.69%
Lung Abscess (pus in lungs): 1 person, 7.69%
Gastric Ulcer (stomach ulcer): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Solu-medrol and have Lower extremity mass?

- Check whether Lower extremity mass is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Solu-medrol:

Solu-medrol (39,410 reports)

Lower extremity mass treatments and more:

Lower extremity mass (860 reports)

How severe was Lower extremity mass and when was it recovered:

Lower extremity mass in Solu-medrol

Expand to all the drugs that have ingredients of methylprednisolone sodium succinate:

Lower extremity mass and drugs with ingredients of methylprednisolone sodium succinate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Solu-medrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lower extremity mass:

Lower extremity mass (168 drugs)

Browse all the conditions that are associated with Lower extremity mass:

Lower extremity mass (298 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methylprednisolone sodium succinate (the active ingredients of Solu-medrol) and Solu-medrol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.