Solu-medrol and Muscle function loss - a phase IV clinical study of FDA data

Summary:

Muscle function loss is reported as a side effect among people who take Solu-medrol (methylprednisolone sodium succinate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Tysabri, and have Psoriasis.

The phase IV clinical study analyzes which people have Muscle function loss when taking Solu-medrol. It is created by eHealthMe based on reports of 39,265 people who have side effects when taking Solu-medrol from the FDA, and is updated regularly.

What is Solu-medrol?

Solu-medrol has active ingredients of methylprednisolone sodium succinate. It is often used in multiple sclerosis. eHealthMe is studying from 39,410 Solu-medrol users. Check the latest studies of Solu-medrol.

What is Muscle function loss?

Muscle function loss is found to be associated with 1,001 drugs and 1,521 conditions by eHealthMe. Check the latest studies of Muscle function loss.

On Jul, 12, 2026

39,265 people reported to have side effects when taking Solu-medrol.
Among them, 74 people (0.19%) have Muscle function loss.

Could Solu-medrol cause Muscle function loss?

Among these 74 people:

How long have people been on Solu-medrol when they have Muscle function loss? *

What is the gender of people who have Muscle function loss when taking Solu-medrol? *

female: 68.49 %
male: 31.51 %

What is the age of people who have Muscle function loss when taking Solu-medrol? *

What are other drugs people take besides Solu-medrol? *

What are other side effects people have besides Muscle function loss? *

Weakness: 23 people, 31.08%
Headache (pain in head): 14 people, 18.92%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 13 people, 17.57%
High Blood Pressure: 13 people, 17.57%
Pain In Extremity: 13 people, 17.57%
Hypoaesthesia (reduced sense of touch or sensation): 12 people, 16.22%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 11 people, 14.86%
Acute Kidney Failure: 11 people, 14.86%
Dizziness: 11 people, 14.86%
Fatigue (feeling of tiredness): 10 people, 13.51%

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 6 people, 8.11%
Nausea (feeling of having an urge to vomit): 5 people, 6.76%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 6.76%
Gastroenteritis (inflammation of stomach and intestine): 5 people, 6.76%
Migraine (headache): 5 people, 6.76%
Diarrhea: 5 people, 6.76%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 6.76%
Staphylococcal Infection (an infection with staphylococcus bacteria): 5 people, 6.76%
Bacterial Infection: 5 people, 6.76%
Urinary Tract Infection: 5 people, 6.76%

* Approximation only. Some reports may have incomplete information.

Do you take Solu-medrol and have Muscle function loss?

- Check whether Muscle function loss is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Solu-medrol:

Solu-medrol (39,410 reports)

Muscle function loss treatments and more:

Muscle function loss (17,723 reports)

How severe was Muscle function loss and when was it recovered:

Muscle function loss in Solu-medrol

Expand to all the drugs that have ingredients of methylprednisolone sodium succinate:

Muscle function loss and drugs with ingredients of methylprednisolone sodium succinate (247 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Solu-medrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle function loss:

Muscle function loss (1,001 drugs)

Browse all the conditions that are associated with Muscle function loss:

Muscle function loss (1,521 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methylprednisolone sodium succinate (the active ingredients of Solu-medrol) and Solu-medrol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.