Solu-medrol and Peripheral ischaemia - a phase IV clinical study of FDA data

Summary:

Peripheral ischaemia is reported as a side effect among people who take Solu-medrol (methylprednisolone sodium succinate), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Vitamin B12, and have Neuralgia.

The phase IV clinical study analyzes which people have Peripheral ischaemia when taking Solu-medrol. It is created by eHealthMe based on reports of 39,265 people who have side effects when taking Solu-medrol from the FDA, and is updated regularly.

What is Solu-medrol?

Solu-medrol has active ingredients of methylprednisolone sodium succinate. It is often used in multiple sclerosis. eHealthMe is studying from 39,410 Solu-medrol users. Check the latest studies of Solu-medrol.

What is Peripheral ischaemia?

Peripheral ischaemia (impaired circulation to an extremity) is found to be associated with 574 drugs and 645 conditions by eHealthMe. Check the latest studies of Peripheral ischaemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

39,265 people reported to have side effects when taking Solu-medrol.
Among them, 34 people (0.09%) have Peripheral ischaemia.

Could Solu-medrol cause Peripheral ischaemia?

Among these 34 people:

How long have people been on Solu-medrol when they have Peripheral ischaemia? *

What is the gender of people who have Peripheral ischaemia when taking Solu-medrol? *

female: 61.76 %
male: 38.24 %

What is the age of people who have Peripheral ischaemia when taking Solu-medrol? *

What are other drugs people take besides Solu-medrol? *

What are other side effects people have besides Peripheral ischaemia? *

Hypoaesthesia (reduced sense of touch or sensation): 10 people, 29.41%
Pain In Extremity: 10 people, 29.41%
Skin Discoloration: 10 people, 29.41%
Blockage Of Leg Arteries: 9 people, 26.47%
Dizziness: 9 people, 26.47%
Peripheral Coldness: 9 people, 26.47%
Stress And Anxiety: 9 people, 26.47%
Insomnia (sleeplessness): 9 people, 26.47%
Weakness: 9 people, 26.47%
Radial Pulse Abnormal (abnormal pulse): 8 people, 23.53%

What are the existing conditions these people have? *

Neuralgia (pain in one or more nerves): 6 people, 17.65%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 8.82%
High Blood Pressure: 2 people, 5.88%
Skin Disorder (skin disease): 2 people, 5.88%
Neoplasm Malignant (cancer tumour): 2 people, 5.88%
Colitis (inflammation of colon): 2 people, 5.88%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 5.88%
Wegener's Granulomatosis (inflammation of the blood vessels lungs sinuses): 1 person, 2.94%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 2.94%
Depression: 1 person, 2.94%

* Approximation only. Some reports may have incomplete information.

Do you take Solu-medrol and have Peripheral ischaemia?

- Check whether Peripheral ischaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Solu-medrol:

Solu-medrol (39,410 reports)

Peripheral ischaemia treatments and more:

Peripheral ischaemia (5,405 reports)

How severe was Peripheral ischaemia and when was it recovered:

Peripheral ischaemia in Solu-medrol

Expand to all the drugs that have ingredients of methylprednisolone sodium succinate:

Peripheral ischaemia and drugs with ingredients of methylprednisolone sodium succinate (77 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Solu-medrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Peripheral ischaemia:

Peripheral ischaemia (574 drugs)

Browse all the conditions that are associated with Peripheral ischaemia:

Peripheral ischaemia (645 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methylprednisolone sodium succinate (the active ingredients of Solu-medrol) and Solu-medrol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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