Soma and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Soma (carisoprodol), especially for people who are female, 50-59 old, have been taking the drug for 10+ years also take Vicodin, and have Osteoporosis.

The phase IV clinical study analyzes which people have Sciatica when taking Soma. It is created by eHealthMe based on reports of 15,632 people who have side effects when taking Soma from the FDA, and is updated regularly.

What is Soma?

Soma has active ingredients of carisoprodol. It is often used in muscle spasms. eHealthMe is studying from 17,136 Soma users. Check the latest studies of Soma.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,155 drugs and 1,415 conditions by eHealthMe. Check the latest studies of Sciatica.

On Oct, 02, 2025

15,632 people reported to have side effects when taking Soma.
Among them, 89 people (0.57%) have Sciatica.

Among these 89 people:

How long have people been on Soma when they have Sciatica? *

What is the gender of people who have Sciatica when taking Soma? *

female: 65.12 %
male: 34.88 %

What is the age of people who have Sciatica when taking Soma? *

What are other drugs people take besides Soma? *

What are other side effects people have besides Sciatica? *

Stress And Anxiety: 35 people, 39.33%
High Blood Pressure: 35 people, 39.33%
Depression: 31 people, 34.83%
Weakness: 31 people, 34.83%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 30 people, 33.71%
Pain In Extremity: 29 people, 32.58%
Fall: 28 people, 31.46%
Neck Pain: 24 people, 26.97%
Dyspnea (difficult or laboured breathing): 24 people, 26.97%
Nausea (feeling of having an urge to vomit): 23 people, 25.84%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 8 people, 8.99%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 7.87%
Menopause (end of monthly cycles in women): 7 people, 7.87%
Depression: 6 people, 6.74%
Neuralgia (pain in one or more nerves): 4 people, 4.49%
Osteopenia (a condition where bone mineral density is lower than normal): 4 people, 4.49%
Hypersensitivity: 4 people, 4.49%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 4.49%
Prostate Cancer: 4 people, 4.49%
Breakthrough Pain: 3 people, 3.37%

* Approximation only. Some reports may have incomplete information.

Do you take Soma and have Sciatica?

- Check whether Sciatica is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Soma:

Soma (17,136 reports)

Sciatica treatments and more:

Sciatica (28,503 reports)

How severe was Sciatica and when was it recovered:

Sciatica in Soma

Browse all side effects of Soma:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica:

Sciatica (1,155 drugs)

Browse all the conditions that are associated with Sciatica:

Sciatica (1,415 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on carisoprodol (the active ingredients of Soma) and Soma (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.